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Page 1
1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads.
Rombouts FJ, Tresadern G, Delgado O, Martínez-Lamenca C, Van Gool M, García-Molina A, Alonso de Diego SA, Oehlrich D, Prokopcova H, Alonso JM, Austin N, Borghys H, Van Brandt S, Surkyn M, De Cleyn M, Vos A, Alexander R, Macdonald G, Moechars D, Gijsen H, Trabanco AA. Rombouts FJ, et al. Among authors: garcia molina a. J Med Chem. 2015 Oct 22;58(20):8216-35. doi: 10.1021/acs.jmedchem.5b01101. Epub 2015 Oct 10. J Med Chem. 2015. PMID: 26378740
Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate.
Gijsen HJM, Alonso de Diego SA, De Cleyn M, García-Molina A, Macdonald GJ, Martínez-Lamenca C, Oehlrich D, Prokopcova H, Rombouts FJR, Surkyn M, Trabanco AA, Van Brandt S, Van den Bossche D, Van Gool M, Austin N, Borghys H, Dhuyvetter D, Moechars D. Gijsen HJM, et al. Among authors: garcia molina a. J Med Chem. 2018 Jun 28;61(12):5292-5303. doi: 10.1021/acs.jmedchem.8b00304. Epub 2018 Jun 11. J Med Chem. 2018. PMID: 29809004
Inhibition of the Alanine-Serine-Cysteine-1 Transporter by BMS-466442.
Torrecillas IR, Conde-Ceide S, de Lucas AI, Garcı A Molina A, Trabanco AA, Lavreysen H, Pardo L, Tresadern G. Torrecillas IR, et al. ACS Chem Neurosci. 2019 May 15;10(5):2510-2517. doi: 10.1021/acschemneuro.9b00019. Epub 2019 Mar 14. ACS Chem Neurosci. 2019. PMID: 30821959
Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders.
Martínez-Viturro CM, Trabanco AA, Royes J, Fernández E, Tresadern G, Vega JA, Del Cerro A, Delgado F, García Molina A, Tovar F, Shaffer P, Ebneth A, Bretteville A, Mertens L, Somers M, Alonso JM, Bartolomé-Nebreda JM. Martínez-Viturro CM, et al. Among authors: garcia molina a. J Med Chem. 2020 Nov 25;63(22):14017-14044. doi: 10.1021/acs.jmedchem.0c01479. Epub 2020 Nov 16. J Med Chem. 2020. PMID: 33197187
Discovery of 6,7-Dihydropyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives as mGluR2 Negative Allosteric Modulators with In Vivo Activity in a Rodent's Model of Cognition.
Alonso de Diego SA, Linares ML, García Molina A, de Lucas AI, Del Cerro A, Alonso JM, Ver Donck L, Cid JM, Trabanco AA, Van Gool M. Alonso de Diego SA, et al. Among authors: garcia molina a. J Med Chem. 2024 Sep 12;67(17):15569-15585. doi: 10.1021/acs.jmedchem.4c01227. Epub 2024 Aug 29. J Med Chem. 2024. PMID: 39208150
Correction to Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate.
Gijsen HJM, Alonso de Diego SA, De Cleyn M, García-Molina A, Macdonald GJ, Martinez-Lamenca C, Oehlrich D, Prokopcova H, Rombouts FJR, Surkyn M, Trabanco AA, Van Brandt S, Van den Bossche D, Van Gool M, Austin N, Borghys H, Dhuyvetter D, Urmaliya V, Teisman A, Moechars D. Gijsen HJM, et al. Among authors: garcia molina a. J Med Chem. 2018 Dec 27;61(24):11415. doi: 10.1021/acs.jmedchem.8b01859. Epub 2018 Dec 7. J Med Chem. 2018. PMID: 30525600 No abstract available.
Understanding and enhancing post-stroke recovery: Insights from a nested qualitative study within the MindFit Project randomized clinical trial.
Bermudo-Gallaguet A, Bielsa-Pascual J, García-Sierra R, Feijoo-Cid M, Arreciado Marañon A, Ariza M, Agudelo D, Camins-Vila N, Boldó M, Durà Mata MJ, García-Molina A, Torán-Monserrat P, Mataró M. Bermudo-Gallaguet A, et al. Among authors: garcia molina a. Complement Ther Med. 2024 Dec;87:103100. doi: 10.1016/j.ctim.2024.103100. Epub 2024 Oct 11. Complement Ther Med. 2024. PMID: 39396801 Free article. Clinical Trial.
The role of the Arabidopsis tandem zinc-finger C3H15 protein in metal homeostasis.
Andrés-Bordería A, Mazuque-Pons L, Romeu-Perales M, Garcia-Molina A, Andrés-Colás N, Martínez-Pastor MT, Sanz A, Puig S, Peñarrubia L, Perea-García A. Andrés-Bordería A, et al. Among authors: garcia molina a. Plant Physiol Biochem. 2024 Nov;216:109123. doi: 10.1016/j.plaphy.2024.109123. Epub 2024 Sep 11. Plant Physiol Biochem. 2024. PMID: 39276674 Free article.
135 results