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Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming.
De Simone G, Andreata F, Bleriot C, Fumagalli V, Laura C, Garcia-Manteiga JM, Di Lucia P, Gilotto S, Ficht X, De Ponti FF, Bono EB, Giustini L, Ambrosi G, Mainetti M, Zordan P, Bénéchet AP, Ravà M, Chakarov S, Moalli F, Bajenoff M, Guidotti LG, Ginhoux F, Iannacone M. De Simone G, et al. Among authors: de ponti ff. Immunity. 2021 Sep 14;54(9):2089-2100.e8. doi: 10.1016/j.immuni.2021.05.005. Epub 2021 Aug 31. Immunity. 2021. PMID: 34469774 Free PMC article.
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming.
Bénéchet AP, De Simone G, Di Lucia P, Cilenti F, Barbiera G, Le Bert N, Fumagalli V, Lusito E, Moalli F, Bianchessi V, Andreata F, Zordan P, Bono E, Giustini L, Bonilla WV, Bleriot C, Kunasegaran K, Gonzalez-Aseguinolaza G, Pinschewer DD, Kennedy PTF, Naldini L, Kuka M, Ginhoux F, Cantore A, Bertoletti A, Ostuni R, Guidotti LG, Iannacone M. Bénéchet AP, et al. Among authors: de simone g. Nature. 2019 Oct;574(7777):200-205. doi: 10.1038/s41586-019-1620-6. Epub 2019 Oct 2. Nature. 2019. PMID: 31582858 Free PMC article.
A subset of Kupffer cells regulates metabolism through the expression of CD36.
Blériot C, Barreby E, Dunsmore G, Ballaire R, Chakarov S, Ficht X, De Simone G, Andreata F, Fumagalli V, Guo W, Wan G, Gessain G, Khalilnezhad A, Zhang XM, Ang N, Chen P, Morgantini C, Azzimato V, Kong WT, Liu Z, Pai R, Lum J, Shihui F, Low I, Xu C, Malleret B, Kairi MFM, Balachander A, Cexus O, Larbi A, Lee B, Newell EW, Ng LG, Phoo WW, Sobota RM, Sharma A, Howland SW, Chen J, Bajenoff M, Yvan-Charvet L, Venteclef N, Iannacone M, Aouadi M, Ginhoux F. Blériot C, et al. Among authors: de simone g. Immunity. 2021 Sep 14;54(9):2101-2116.e6. doi: 10.1016/j.immuni.2021.08.006. Epub 2021 Aug 31. Immunity. 2021. PMID: 34469775 Free article.
Isolation of mouse Kupffer cells for phenotypic and functional studies.
Andreata F, Blériot C, Di Lucia P, De Simone G, Fumagalli V, Ficht X, Beccaria CG, Kuka M, Ginhoux F, Iannacone M. Andreata F, et al. Among authors: de simone g. STAR Protoc. 2021 Sep 14;2(4):100831. doi: 10.1016/j.xpro.2021.100831. eCollection 2021 Dec 17. STAR Protoc. 2021. PMID: 34585164 Free PMC article.
Here, we provide detailed protocols for the isolation of mouse Kupffer cells - the liver-resident macrophages - for phenotypic (e.g., via flow cytometry, mass cytometry, or RNA-sequencing) analyses or for functional experiments involving cell culture. ...For complete detai …
Here, we provide detailed protocols for the isolation of mouse Kupffer cells - the liver-resident macrophages - for phenotypic (e.g., …
Two recent European guidelines on hypertension.
Verdecchia P, Angeli F, Pucci G, de Simone G, Reboldi G. Verdecchia P, et al. Among authors: de simone g. Eur J Intern Med. 2024 Oct 27:S0953-6205(24)00430-8. doi: 10.1016/j.ejim.2024.10.011. Online ahead of print. Eur J Intern Med. 2024. PMID: 39467730 No abstract available.
915 results