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Immune responses in COVID-19 respiratory tract and blood reveal mechanisms of disease severity.
Zhang W, Chua B, Selva K, Kedzierski L, Ashhurst T, Haycroft E, Shoffner S, Hensen L, Boyd D, James F, Mouhtouris E, Kwong J, Chua K, Drewett G, Copaescu A, Dobson J, Rowntree L, Habel J, Allen L, Koay HF, Neil J, Gartner M, Lee C, Andersson P, Seemann T, Sherry N, Amanat F, Krammer F, Londrigan S, Wakim L, King N, Godfrey D, Mackay L, Thomas P, Nicholson S, Arnold K, Chung A, Holmes N, Smibert O, Trubiano J, Gordon C, Nguyen T, Kedzierska K. Zhang W, et al. Among authors: hensen l. Res Sq [Preprint]. 2021 Aug 26:rs.3.rs-802084. doi: 10.21203/rs.3.rs-802084/v1. Res Sq. 2021. Update in: Nat Commun. 2022 May 19;13(1):2774. doi: 10.1038/s41467-022-30088-y. PMID: 34462740 Free PMC article. Updated. Preprint.
pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs.
Gerlach T, Hensen L, Matrosovich T, Bergmann J, Winkler M, Peteranderl C, Klenk HD, Weber F, Herold S, Pöhlmann S, Matrosovich M. Gerlach T, et al. Among authors: hensen l. J Virol. 2017 May 12;91(11):e00246-17. doi: 10.1128/JVI.00246-17. Print 2017 Jun 1. J Virol. 2017. PMID: 28356532 Free PMC article.
Viral burden, inflammatory milieu and CD8+ T-cell responses to influenza virus in a second-generation thiazolide (RM-5061) and oseltamivir combination therapy study.
Nüssing S, Mifsud E, Hensen L, Koutsakos M, Wang Z, Kedzierski L, Mercuri F, Rossignol JF, Hurt AC, Kedzierska K. Nüssing S, et al. Among authors: hensen l. Influenza Other Respir Viruses. 2020 Nov;14(6):678-687. doi: 10.1111/irv.12776. Epub 2020 Jun 25. Influenza Other Respir Viruses. 2020. PMID: 32588557 Free PMC article.
Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype.
Habel JR, Nguyen THO, van de Sandt CE, Juno JA, Chaurasia P, Wragg K, Koutsakos M, Hensen L, Jia X, Chua B, Zhang W, Tan HX, Flanagan KL, Doolan DL, Torresi J, Chen W, Wakim LM, Cheng AC, Doherty PC, Petersen J, Rossjohn J, Wheatley AK, Kent SJ, Rowntree LC, Kedzierska K. Habel JR, et al. Among authors: hensen l. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24384-24391. doi: 10.1073/pnas.2015486117. Epub 2020 Sep 10. Proc Natl Acad Sci U S A. 2020. PMID: 32913053 Free PMC article.
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses.
Koutsakos M, Rowntree LC, Hensen L, Chua BY, van de Sandt CE, Habel JR, Zhang W, Jia X, Kedzierski L, Ashhurst TM, Putri GH, Marsh-Wakefield F, Read MN, Edwards DN, Clemens EB, Wong CY, Mordant FL, Juno JA, Amanat F, Audsley J, Holmes NE, Gordon CL, Smibert OC, Trubiano JA, Hughes CM, Catton M, Denholm JT, Tong SYC, Doolan DL, Kotsimbos TC, Jackson DC, Krammer F, Godfrey DI, Chung AW, King NJC, Lewin SR, Wheatley AK, Kent SJ, Subbarao K, McMahon J, Thevarajan I, Nguyen THO, Cheng AC, Kedzierska K. Koutsakos M, et al. Among authors: hensen l. Cell Rep Med. 2021 Mar 16;2(3):100208. doi: 10.1016/j.xcrm.2021.100208. Epub 2021 Feb 5. Cell Rep Med. 2021. PMID: 33564749 Free PMC article.
49 results