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Immune responses in COVID-19 respiratory tract and blood reveal mechanisms of disease severity.
Zhang W, Chua B, Selva K, Kedzierski L, Ashhurst T, Haycroft E, Shoffner S, Hensen L, Boyd D, James F, Mouhtouris E, Kwong J, Chua K, Drewett G, Copaescu A, Dobson J, Rowntree L, Habel J, Allen L, Koay HF, Neil J, Gartner M, Lee C, Andersson P, Seemann T, Sherry N, Amanat F, Krammer F, Londrigan S, Wakim L, King N, Godfrey D, Mackay L, Thomas P, Nicholson S, Arnold K, Chung A, Holmes N, Smibert O, Trubiano J, Gordon C, Nguyen T, Kedzierska K. Zhang W, et al. Among authors: gordon c. Res Sq [Preprint]. 2021 Aug 26:rs.3.rs-802084. doi: 10.21203/rs.3.rs-802084/v1. Res Sq. 2021. Update in: Nat Commun. 2022 May 19;13(1):2774. doi: 10.1038/s41467-022-30088-y. PMID: 34462740 Free PMC article. Updated. Preprint.
Analysis of Skin-Resident Memory T Cells Following Drug Hypersensitivity Reactions.
Trubiano JA, Gordon CL, Castellucci C, Christo SN, Park SL, Mouhtouris E, Konvinse K, Rose M, Goh M, Boyd AS, Phillips EJ, Mackay LK. Trubiano JA, et al. Among authors: gordon cl. J Invest Dermatol. 2020 Jul;140(7):1442-1445.e4. doi: 10.1016/j.jid.2019.11.020. Epub 2019 Dec 26. J Invest Dermatol. 2020. PMID: 31883960 Free PMC article. No abstract available.
COVID-MATCH65-A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2.
Trubiano JA, Vogrin S, Smibert OC, Marhoon N, Alexander AA, Chua KYL, James FL, Jones NRL, Grigg SE, Xu CLH, Moini N, Stanley SR, Birrell MT, Rose MT, Gordon CL, Kwong JC, Holmes NE. Trubiano JA, et al. Among authors: gordon cl. PLoS One. 2020 Dec 9;15(12):e0243414. doi: 10.1371/journal.pone.0243414. eCollection 2020. PLoS One. 2020. PMID: 33296409 Free PMC article.
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses.
Koutsakos M, Rowntree LC, Hensen L, Chua BY, van de Sandt CE, Habel JR, Zhang W, Jia X, Kedzierski L, Ashhurst TM, Putri GH, Marsh-Wakefield F, Read MN, Edwards DN, Clemens EB, Wong CY, Mordant FL, Juno JA, Amanat F, Audsley J, Holmes NE, Gordon CL, Smibert OC, Trubiano JA, Hughes CM, Catton M, Denholm JT, Tong SYC, Doolan DL, Kotsimbos TC, Jackson DC, Krammer F, Godfrey DI, Chung AW, King NJC, Lewin SR, Wheatley AK, Kent SJ, Subbarao K, McMahon J, Thevarajan I, Nguyen THO, Cheng AC, Kedzierska K. Koutsakos M, et al. Among authors: gordon cl. Cell Rep Med. 2021 Mar 16;2(3):100208. doi: 10.1016/j.xcrm.2021.100208. Epub 2021 Feb 5. Cell Rep Med. 2021. PMID: 33564749 Free PMC article.
Adaptive immunity to human coronaviruses is widespread but low in magnitude.
Tan HX, Lee WS, Wragg KM, Nelson C, Esterbauer R, Kelly HG, Amarasena T, Jones R, Starkey G, Wang BZ, Yoshino O, Tiang T, Grayson ML, Opdam H, D'Costa R, Vago A; Austin Liver Transplant Perfusionist Group; Mackay LK, Gordon CL, Wheatley AK, Kent SJ, Juno JA. Tan HX, et al. Among authors: gordon cl. Clin Transl Immunology. 2021 Mar 17;10(3):e1264. doi: 10.1002/cti2.1264. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33747512 Free PMC article.
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity.
Nguyen THO, Rowntree LC, Petersen J, Chua BY, Hensen L, Kedzierski L, van de Sandt CE, Chaurasia P, Tan HX, Habel JR, Zhang W, Allen LF, Earnest L, Mak KY, Juno JA, Wragg K, Mordant FL, Amanat F, Krammer F, Mifsud NA, Doolan DL, Flanagan KL, Sonda S, Kaur J, Wakim LM, Westall GP, James F, Mouhtouris E, Gordon CL, Holmes NE, Smibert OC, Trubiano JA, Cheng AC, Harcourt P, Clifton P, Crawford JC, Thomas PG, Wheatley AK, Kent SJ, Rossjohn J, Torresi J, Kedzierska K. Nguyen THO, et al. Among authors: gordon cl. Immunity. 2021 May 11;54(5):1066-1082.e5. doi: 10.1016/j.immuni.2021.04.009. Epub 2021 Apr 15. Immunity. 2021. PMID: 33951417 Free PMC article.
2,665 results