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LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.
Hu Q, Li C, Wang S, Li Y, Wen B, Zhang Y, Liang K, Yao J, Ye Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Hawke DH, Marks JR, Han L, Hung MC, Zhang B, Lin C, Yang L. Hu Q, et al. Among authors: egranov sd. Cell Res. 2019 Apr;29(4):286-304. doi: 10.1038/s41422-018-0134-3. Epub 2019 Jan 10. Cell Res. 2019. PMID: 30631154 Free PMC article.
PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.
Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Ambati CR, Putluri N, Hawke DH, Han L, Hung MC, Danesh FR, Yang L, Lin C. Li Y, et al. Among authors: egranov sd. J Clin Invest. 2019 Mar 1;129(3):1129-1151. doi: 10.1172/JCI121987. Epub 2019 Feb 11. J Clin Invest. 2019. PMID: 30741721 Free PMC article.
Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.
Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR, Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han L, Lin C, Yang L. Hu Q, et al. Among authors: egranov sd. Nat Immunol. 2019 Jul;20(7):835-851. doi: 10.1038/s41590-019-0400-7. Epub 2019 Jun 3. Nat Immunol. 2019. PMID: 31160797 Free PMC article.
Long noncoding RNA loss in immune suppression in cancer.
Hu Q, Egranov SD, Lin C, Yang L. Hu Q, et al. Among authors: egranov sd. Pharmacol Ther. 2020 Sep;213:107591. doi: 10.1016/j.pharmthera.2020.107591. Epub 2020 May 29. Pharmacol Ther. 2020. PMID: 32473960 Free PMC article. Review.
The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin.
Zhang Y, Li Y, Hu Q, Xi Y, Xing Z, Zhang Z, Huang L, Wu J, Liang K, Nguyen TK, Egranov SD, Sun C, Zhao Z, Hawke DH, Li J, Sun D, Kim JJ, Zhang P, Cheng J, Farida A, Hung MC, Han L, Darabi R, Lin C, Yang L. Zhang Y, et al. Among authors: egranov sd. Nat Cell Biol. 2020 Nov;22(11):1332-1345. doi: 10.1038/s41556-020-00595-5. Epub 2020 Oct 26. Nat Cell Biol. 2020. PMID: 33106653 Free PMC article.
A noncoding RNA modulator potentiates phenylalanine metabolism in mice.
Li Y, Tan Z, Zhang Y, Zhang Z, Hu Q, Liang K, Jun Y, Ye Y, Li YC, Li C, Liao L, Xu J, Xing Z, Pan Y, Chatterjee SS, Nguyen TK, Hsiao H, Egranov SD, Putluri N, Coarfa C, Hawke DH, Gunaratne PH, Tsai KL, Han L, Hung MC, Calin GA, Namour F, Guéant JL, Muntau AC, Blau N, Sutton VR, Schiff M, Feillet F, Zhang S, Lin C, Yang L. Li Y, et al. Among authors: egranov sd. Science. 2021 Aug 6;373(6555):662-673. doi: 10.1126/science.aba4991. Science. 2021. PMID: 34353949 Free PMC article.
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