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Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity.
Meng F, Yu Z, Zhang D, Chen S, Guan H, Zhou R, Wu Q, Zhang Q, Liu S, Venkat Ramani MK, Yang B, Ba XQ, Zhang J, Huang J, Bai X, Qin J, Feng XH, Ouyang S, Zhang YJ, Liang T, Xu P. Meng F, et al. Among authors: liu s. Mol Cell. 2021 Oct 21;81(20):4147-4164.e7. doi: 10.1016/j.molcel.2021.07.040. Epub 2021 Aug 27. Mol Cell. 2021. PMID: 34453890 Free article.
Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation.
Meng F, Zhou R, Wu S, Zhang Q, Jin Q, Zhou Y, Plouffe SW, Liu S, Song H, Xia Z, Zhao B, Ye S, Feng XH, Guan KL, Zou J, Xu P. Meng F, et al. Among authors: liu s. Genes Dev. 2016 May 1;30(9):1086-100. doi: 10.1101/gad.277533.116. Epub 2016 Apr 28. Genes Dev. 2016. PMID: 27125670 Free PMC article.
AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity.
Zhang Q, Liu S, Zhang CS, Wu Q, Yu X, Zhou R, Meng F, Wang A, Zhang F, Chen S, Wang X, Li L, Huang J, Huang YW, Zou J, Qin J, Liang T, Feng XH, Lin SC, Xu P. Zhang Q, et al. Among authors: liu s. Mol Cell. 2022 Dec 1;82(23):4519-4536.e7. doi: 10.1016/j.molcel.2022.10.026. Epub 2022 Nov 15. Mol Cell. 2022. PMID: 36384137 Free article.
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