Chen S - Search Results

1

Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity.

Meng F, Yu Z, Zhang D, Chen S, Guan H, Zhou R, Wu Q, Zhang Q, Liu S, Venkat Ramani MK, Yang B, Ba XQ, Zhang J, Huang J, Bai X, Qin J, Feng XH, Ouyang S, Zhang YJ, Liang T, Xu P. Meng F, et al. Among authors: chen s. Mol Cell. 2021 Oct 21;81(20):4147-4164.e7. doi: 10.1016/j.molcel.2021.07.040. Epub 2021 Aug 27. Mol Cell. 2021. PMID: 34453890 Free article.

2

Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade.

Zhang Q, Meng F, Chen S, Plouffe SW, Wu S, Liu S, Li X, Zhou R, Wang J, Zhao B, Liu J, Qin J, Zou J, Feng XH, Guan KL, Xu P. Zhang Q, et al. Among authors: chen s. Nat Cell Biol. 2017 Apr;19(4):362-374. doi: 10.1038/ncb3496. Epub 2017 Mar 27. Nat Cell Biol. 2017. PMID: 28346439 Free PMC article.

3

Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses.

Liu S, Chen S, Li X, Wu S, Zhang Q, Jin Q, Hu L, Zhou R, Yu Z, Meng F, Wang S, Huang Y, Ye S, Shen L, Xia Z, Zou J, Feng XH, Xu P. Liu S, et al. Among authors: chen s. Cell Host Microbe. 2017 Jun 14;21(6):754-768.e5. doi: 10.1016/j.chom.2017.05.010. Cell Host Microbe. 2017. PMID: 28618271 Free article.

4

TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology.

Chen S, Liu S, Wang J, Wu Q, Wang A, Guan H, Zhang Q, Zhang D, Wang X, Song H, Qin J, Zou J, Jiang Z, Ouyang S, Feng XH, Liang T, Xu P. Chen S, et al. Mol Cell. 2020 Dec 3;80(5):810-827.e7. doi: 10.1016/j.molcel.2020.10.018. Epub 2020 Nov 9. Mol Cell. 2020. PMID: 33171123 Free article.

5

A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis.

Zhang D, Liu Y, Zhu Y, Zhang Q, Guan H, Liu S, Chen S, Mei C, Chen C, Liao Z, Xi Y, Ouyang S, Feng XH, Liang T, Shen L, Xu P. Zhang D, et al. Among authors: chen s, chen c. Nat Cell Biol. 2022 May;24(5):766-782. doi: 10.1038/s41556-022-00894-z. Epub 2022 May 2. Nat Cell Biol. 2022. PMID: 35501370

6

AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity.

Zhang Q, Liu S, Zhang CS, Wu Q, Yu X, Zhou R, Meng F, Wang A, Zhang F, Chen S, Wang X, Li L, Huang J, Huang YW, Zou J, Qin J, Liang T, Feng XH, Lin SC, Xu P. Zhang Q, et al. Among authors: chen s. Mol Cell. 2022 Dec 1;82(23):4519-4536.e7. doi: 10.1016/j.molcel.2022.10.026. Epub 2022 Nov 15. Mol Cell. 2022. PMID: 36384137 Free article.

7

Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders.

Wang A, Chen C, Mei C, Liu S, Xiang C, Fang W, Zhang F, Xu Y, Chen S, Zhang Q, Bai X, Lin A, Neculai D, Xia B, Ye C, Zou J, Liang T, Feng XH, Li X, Shen C, Xu P. Wang A, et al. Among authors: chen c, chen s. Nat Cell Biol. 2024 Feb;26(2):219-234. doi: 10.1038/s41556-023-01339-x. Epub 2024 Jan 22. Nat Cell Biol. 2024. PMID: 38253667

8

SLAM-family receptors promote resolution of ILC2-mediated inflammation.

Wang Y, Quan Y, He J, Chen S, Dong Z. Wang Y, et al. Among authors: chen s. Nat Commun. 2024 Jun 13;15(1):5056. doi: 10.1038/s41467-024-49466-9. Nat Commun. 2024. PMID: 38871792 Free PMC article.

9

Unleashing a safe and potent pro-senescence anti-tumor strategy.

Chen S, Sun B, Dong Z. Chen S, et al. Cancer Cell. 2024 Apr 8;42(4):504-507. doi: 10.1016/j.ccell.2024.02.003. Epub 2024 Feb 29. Cancer Cell. 2024. PMID: 38428411

10

Combined deficiency of SLAMF8 and SLAMF9 prevents endotoxin-induced liver inflammation by downregulating TLR4 expression on macrophages.

Zeng X, Liu G, Peng W, He J, Cai C, Xiong W, Chen S, Yang M, Dong Z. Zeng X, et al. Among authors: chen s. Cell Mol Immunol. 2020 Feb;17(2):153-162. doi: 10.1038/s41423-018-0191-z. Epub 2018 Dec 14. Cell Mol Immunol. 2020. PMID: 30552382 Free PMC article.

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