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Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion.
Jahrsdörfer B, Vollmer A, Blackwell SE, Maier J, Sontheimer K, Beyer T, Mandel B, Lunov O, Tron K, Nienhaus GU, Simmet T, Debatin KM, Weiner GJ, Fabricius D. Jahrsdörfer B, et al. Among authors: fabricius d. Blood. 2010 Feb 11;115(6):1156-65. doi: 10.1182/blood-2009-07-235382. Epub 2009 Dec 3. Blood. 2010. PMID: 19965634 Free PMC article.
CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B.
Hagn M, Ebel V, Sontheimer K, Schwesinger E, Lunov O, Beyer T, Fabricius D, Barth TF, Viardot A, Stilgenbauer S, Hepp J, Scharffetter-Kochanek K, Simmet T, Jahrsdörfer B. Hagn M, et al. Among authors: fabricius d. Eur J Immunol. 2010 Jul;40(7):2060-9. doi: 10.1002/eji.200940113. Eur J Immunol. 2010. PMID: 20394077 Free article.
Interleukin 21-induced granzyme B-expressing B cells infiltrate tumors and regulate T cells.
Lindner S, Dahlke K, Sontheimer K, Hagn M, Kaltenmeier C, Barth TF, Beyer T, Reister F, Fabricius D, Lotfi R, Lunov O, Nienhaus GU, Simmet T, Kreienberg R, Möller P, Schrezenmeier H, Jahrsdörfer B. Lindner S, et al. Among authors: fabricius d. Cancer Res. 2013 Apr 15;73(8):2468-79. doi: 10.1158/0008-5472.CAN-12-3450. Epub 2013 Feb 5. Cancer Res. 2013. PMID: 23384943
CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients.
Kaltenmeier C, Gawanbacht A, Beyer T, Lindner S, Trzaska T, van der Merwe JA, Härter G, Grüner B, Fabricius D, Lotfi R, Schwarz K, Schütz C, Hönig M, Schulz A, Kern P, Bommer M, Schrezenmeier H, Kirchhoff F, Jahrsdörfer B. Kaltenmeier C, et al. Among authors: fabricius d. J Immunol. 2015 Apr 15;194(8):3768-77. doi: 10.4049/jimmunol.1402568. Epub 2015 Mar 16. J Immunol. 2015. PMID: 25780036
41 results