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Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer.
Bosch-Barrera J, Verdura S, Ruffinelli JC, Carcereny E, Sais E, Cuyàs E, Palmero R, Lopez-Bonet E, Hernández-Martínez A, Oliveras G, Buxó M, Izquierdo A, Morán T, Nadal E, Menendez JA. Bosch-Barrera J, et al. Among authors: cuyas e. Cancers (Basel). 2021 Aug 19;13(16):4168. doi: 10.3390/cancers13164168. Cancers (Basel). 2021. PMID: 34439322 Free PMC article.
The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells.
Menendez JA, Joven J, Cufí S, Corominas-Faja B, Oliveras-Ferraros C, Cuyàs E, Martin-Castillo B, López-Bonet E, Alarcón T, Vazquez-Martin A. Menendez JA, et al. Among authors: cuyas e. Cell Cycle. 2013 Apr 15;12(8):1166-79. doi: 10.4161/cc.24479. Epub 2013 Apr 2. Cell Cycle. 2013. PMID: 23549172 Free PMC article.
Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells.
Cufí S, Bonavia R, Vazquez-Martin A, Corominas-Faja B, Oliveras-Ferraros C, Cuyàs E, Martin-Castillo B, Barrajón-Catalán E, Visa J, Segura-Carretero A, Bosch-Barrera J, Joven J, Micol V, Menendez JA. Cufí S, et al. Among authors: cuyas e. Food Chem Toxicol. 2013 Oct;60:360-8. doi: 10.1016/j.fct.2013.07.063. Epub 2013 Aug 1. Food Chem Toxicol. 2013. PMID: 23916468
Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway.
Corominas-Faja B, Cufí S, Oliveras-Ferraros C, Cuyàs E, López-Bonet E, Lupu R, Alarcón T, Vellon L, Iglesias JM, Leis O, Martín ÁG, Vazquez-Martin A, Menendez JA. Corominas-Faja B, et al. Among authors: cuyas e. Cell Cycle. 2013 Sep 15;12(18):3109-24. doi: 10.4161/cc.26173. Epub 2013 Aug 21. Cell Cycle. 2013. PMID: 23974095 Free PMC article.
Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin.
Cufí S, Corominas-Faja B, Lopez-Bonet E, Bonavia R, Pernas S, López IÁ, Dorca J, Martínez S, López NB, Fernández SD, Cuyàs E, Visa J, Rodríguez-Gallego E, Quirantes-Piné R, Segura-Carretero A, Joven J, Martin-Castillo B, Menendez JA. Cufí S, et al. Among authors: cuyas e. Oncotarget. 2013 Sep;4(9):1484-95. doi: 10.18632/oncotarget.1234. Oncotarget. 2013. PMID: 23986086 Free PMC article.
IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations.
Vazquez-Martin A, Cufí S, Oliveras-Ferraros C, Torres-Garcia VZ, Corominas-Faja B, Cuyàs E, Bonavia R, Visa J, Martin-Castillo B, Barrajón-Catalán E, Micol V, Bosch-Barrera J, Menendez JA. Vazquez-Martin A, et al. Among authors: cuyas e. Sci Rep. 2013;3:2560. doi: 10.1038/srep02560. Sci Rep. 2013. PMID: 23994953 Free PMC article.
Stem cell-like ALDH(bright) cellular states in EGFR-mutant non-small cell lung cancer: a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin.
Corominas-Faja B, Oliveras-Ferraros C, Cuyàs E, Segura-Carretero A, Joven J, Martin-Castillo B, Barrajón-Catalán E, Micol V, Bosch-Barrera J, Menendez JA. Corominas-Faja B, et al. Among authors: cuyas e. Cell Cycle. 2013 Nov 1;12(21):3390-404. doi: 10.4161/cc.26417. Epub 2013 Sep 17. Cell Cycle. 2013. PMID: 24047698 Free PMC article.
100 results