Brown DC - Search Results

1

Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials.

Iadarola MJ, Brown DC, Nahama A, Sapio MR, Mannes AJ. Iadarola MJ, et al. Among authors: brown dc. Front Pharmacol. 2021 Aug 5;12:705743. doi: 10.3389/fphar.2021.705743. eCollection 2021. Front Pharmacol. 2021. PMID: 34421597 Free PMC article. Review.

2

Long-term pain relief in canine osteoarthritis by a single intra-articular injection of resiniferatoxin, a potent TRPV1 agonist.

Iadarola MJ, Sapio MR, Raithel SJ, Mannes AJ, Brown DC. Iadarola MJ, et al. Among authors: brown dc. Pain. 2018 Oct;159(10):2105-2114. doi: 10.1097/j.pain.0000000000001314. Pain. 2018. PMID: 30015705 Free PMC article.

3

Intrathecal resiniferatoxin in a dog model: efficacy in bone cancer pain.

Brown DC, Agnello K, Iadarola MJ. Brown DC, et al. Pain. 2015 Jun;156(6):1018-1024. doi: 10.1097/j.pain.0000000000000115. Pain. 2015. PMID: 25659068 Free PMC article. Clinical Trial.

4

Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons.

Sapio MR, Neubert JK, LaPaglia DM, Maric D, Keller JM, Raithel SJ, Rohrs EL, Anderson EM, Butman JA, Caudle RM, Brown DC, Heiss JD, Mannes AJ, Iadarola MJ. Sapio MR, et al. Among authors: brown dc. J Clin Invest. 2018 Apr 2;128(4):1657-1670. doi: 10.1172/JCI94331. Epub 2018 Mar 19. J Clin Invest. 2018. PMID: 29408808 Free PMC article.

5

Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model.

Brown DC, Iadarola MJ, Perkowski SZ, Erin H, Shofer F, Laszlo KJ, Olah Z, Mannes AJ. Brown DC, et al. Anesthesiology. 2005 Nov;103(5):1052-9. doi: 10.1097/00000542-200511000-00020. Anesthesiology. 2005. PMID: 16249680 Free article.

6

Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control.

Karai L, Brown DC, Mannes AJ, Connelly ST, Brown J, Gandal M, Wellisch OM, Neubert JK, Olah Z, Iadarola MJ. Karai L, et al. Among authors: brown dc, brown j. J Clin Invest. 2004 May;113(9):1344-52. doi: 10.1172/JCI20449. J Clin Invest. 2004. PMID: 15124026 Free PMC article.

7

Measurement of resiniferatoxin in serum samples by high-performance liquid chromatography.

Mannes AJ, Brown DC, Keller J, Cordes L, Eckenhoff RG, Caudle RM, Iadarola MJ, Meng QC. Mannes AJ, et al. Among authors: brown dc. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Sep 5;823(2):184-8. doi: 10.1016/j.jchromb.2005.06.042. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 16039169

8

Measurement of chronic pain in companion animals: Discussions from the Pain in Animals Workshop (PAW) 2017.

Lascelles BDX, Brown DC, Conzemius MG, Gill M, Oshinsky ML, Sharkey M. Lascelles BDX, et al. Among authors: brown dc. Vet J. 2019 Aug;250:71-78. doi: 10.1016/j.tvjl.2019.07.001. Epub 2019 Jul 3. Vet J. 2019. PMID: 31383423 Review.

9

Measurement of chronic pain in companion animals: Priorities for future research and development based on discussions from the Pain in Animals Workshop (PAW) 2017.

Lascelles BDX, Brown DC, Conzemius M, Gill M, Oshinsky ML, Sharkey M. Lascelles BDX, et al. Among authors: brown dc. Vet J. 2019 Oct;252:105370. doi: 10.1016/j.tvjl.2019.105370. Epub 2019 Aug 28. Vet J. 2019. PMID: 31554586 Review.

10

Spontaneous painful disease in companion animals can facilitate the development of chronic pain therapies for humans.

Lascelles BDX, Brown DC, Maixner W, Mogil JS. Lascelles BDX, et al. Among authors: brown dc. Osteoarthritis Cartilage. 2018 Feb;26(2):175-183. doi: 10.1016/j.joca.2017.11.011. Epub 2017 Nov 24. Osteoarthritis Cartilage. 2018. PMID: 29180098 Free article. Review.

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