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The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia.
Caffall ZF, Wilkes BJ, Hernández-Martinez R, Rittiner JE, Fox JT, Wan KK, Shipman MK, Titus SA, Zhang YQ, Patnaik S, Hall MD, Boxer MB, Shen M, Li Z, Vaillancourt DE, Calakos N. Caffall ZF, et al. Among authors: calakos n. Sci Transl Med. 2021 Aug 18;13(607):eabd3904. doi: 10.1126/scitranslmed.abd3904. Sci Transl Med. 2021. PMID: 34408078 Free PMC article.
Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.
Rittiner JE, Caffall ZF, Hernández-Martinez R, Sanderson SM, Pearson JL, Tsukayama KK, Liu AY, Xiao C, Tracy S, Shipman MK, Hickey P, Johnson J, Scott B, Stacy M, Saunders-Pullman R, Bressman S, Simonyan K, Sharma N, Ozelius LJ, Cirulli ET, Calakos N. Rittiner JE, et al. Among authors: calakos n. Neuron. 2016 Dec 21;92(6):1238-1251. doi: 10.1016/j.neuron.2016.11.012. Epub 2016 Dec 8. Neuron. 2016. PMID: 27939583 Free PMC article.
Seq-ing the Circuit Logic of the Basal Ganglia.
Hernandez-Martinez R, Calakos N. Hernandez-Martinez R, et al. Among authors: calakos n. Trends Neurosci. 2017 Jun;40(6):325-327. doi: 10.1016/j.tins.2017.04.006. Epub 2017 May 10. Trends Neurosci. 2017. PMID: 28501393 Free PMC article.
Defining research priorities in dystonia.
Lungu C, Ozelius L, Standaert D, Hallett M, Sieber BA, Swanson-Fisher C, Berman BD, Calakos N, Moore JC, Perlmutter JS, Pirio Richardson SE, Saunders-Pullman R, Scheinfeldt L, Sharma N, Sillitoe R, Simonyan K, Starr PA, Taylor A, Vitek J; participants and organizers of the NINDS Workshop on Research Priorities in Dystonia. Lungu C, et al. Among authors: calakos n. Neurology. 2020 Mar 24;94(12):526-537. doi: 10.1212/WNL.0000000000009140. Epub 2020 Feb 25. Neurology. 2020. PMID: 32098856 Free PMC article. Review.
51 results