Sane R - Search Results

1

Pharmacokinetics of Ipatasertib in Subjects With Hepatic Impairment Using 2 Methods of Classification of Hepatic Function.

Sane R, Malhi V, Sutaria DS, Cho E, Twomey P, Craggs C, Wang J, Harris A, Musib L. Sane R, et al. J Clin Pharmacol. 2022 Feb;62(2):171-181. doi: 10.1002/jcph.1941. Epub 2021 Dec 23. J Clin Pharmacol. 2022. PMID: 34402068 Free PMC article. Clinical Trial.

2

Calibrating the In Vitro-In Vivo Correlation for OATP-Mediated Drug-Drug Interactions with Rosuvastatin Using Static and PBPK Models.

Sane R, Cheung KWK, Kovács P, Farasyn T, Li R, Bui A, Musib L, Kis E, Plise E, Gáborik Z. Sane R, et al. Drug Metab Dispos. 2020 Dec;48(12):1264-1270. doi: 10.1124/dmd.120.000149. Epub 2020 Oct 9. Drug Metab Dispos. 2020. PMID: 33037044

3

Evaluation of Ipatasertib Interactions with Itraconazole and Coproporphyrin I and III in a Single Drug Interaction Study in Healthy Subjects.

Sane RS, Cheung KWK, Cho E, Liederer BM, Hanover J, Malhi V, Plise E, Wong S, Musib L. Sane RS, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):87-95. doi: 10.1124/jpet.121.000620. Epub 2021 May 28. J Pharmacol Exp Ther. 2021. PMID: 34049965 Clinical Trial.

4

Population Pharmacokinetics of Ipatasertib and Its Metabolite in Cancer Patients.

Yoshida K, Wilkins J, Winkler J, Wade JR, Kotani N, Wang N, Sane R, Chanu P. Yoshida K, et al. Among authors: sane r. J Clin Pharmacol. 2021 Dec;61(12):1579-1591. doi: 10.1002/jcph.1942. Epub 2021 Aug 11. J Clin Pharmacol. 2021. PMID: 34273118 Clinical Trial.

5

Single- and multiple-dose pharmacokinetics, potential for CYP3A inhibition, and food effect in patients with cancer and healthy subjects receiving ipatasertib.

Malhi V, Budha N, Sane R, Huang J, Liederer B, Meng R, Patel P, Deng Y, Cervantes A, Tabernero J, Musib L. Malhi V, et al. Among authors: sane r. Cancer Chemother Pharmacol. 2021 Dec;88(6):921-930. doi: 10.1007/s00280-021-04344-9. Epub 2021 Sep 1. Cancer Chemother Pharmacol. 2021. PMID: 34471960 Clinical Trial.

6

Assessment of cytochrome P450 3A4-mediated drug-drug interactions for ipatasertib using a fit-for-purpose physiologically based pharmacokinetic model.

Jing J, Chen Y, Musib L, Jin JY, Cheung KWK, Yoshida K, Sane R. Jing J, et al. Among authors: sane r. Cancer Chemother Pharmacol. 2022 May;89(5):707-720. doi: 10.1007/s00280-022-04434-2. Epub 2022 Apr 15. Cancer Chemother Pharmacol. 2022. PMID: 35428895 Free PMC article.

7

Mitigating ipatasertib-induced glucose increase through dose and meal timing modifications.

Sutaria DS, Agarwal P, Huang KC, Miles DR, Rotmensch J, Hinton H, Gallo JD, Rasuo G, Sane RS. Sutaria DS, et al. Among authors: sane rs. Clin Transl Sci. 2022 Dec;15(12):2989-2999. doi: 10.1111/cts.13420. Epub 2022 Nov 16. Clin Transl Sci. 2022. PMID: 36197694 Free PMC article. Clinical Trial.

8

Quantitative Prediction of OATP-Mediated Drug-Drug Interactions With Model-Based Analysis of Endogenous Biomarker Kinetics.

Yoshida K, Guo C, Sane R. Yoshida K, et al. Among authors: sane r. CPT Pharmacometrics Syst Pharmacol. 2018 Aug;7(8):517-524. doi: 10.1002/psp4.12315. Epub 2018 Aug 23. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 29924471 Free PMC article.

9

The effect of BI 409306 on heart rate in healthy volunteers: a randomised, double-blind, placebo-controlled, crossover study.

Müller F, Sand M, Wunderlich G, Link J, Schultheis C, Dansirikul C, Sane R, Laszlo R, Steinacker JM. Müller F, et al. Among authors: sane r. Eur J Clin Pharmacol. 2022 May;78(5):801-812. doi: 10.1007/s00228-022-03274-6. Epub 2022 Jan 28. Eur J Clin Pharmacol. 2022. PMID: 35089373 Free PMC article. Clinical Trial.

10

Case Study 6: Deconvoluting Hyperbilirubinemia-Differentiating Between Hepatotoxicity and Reversible Inhibition of UGT1A1, MRP2, or OATP1B1 in Drug Development.

Templeton I, Eichenbaum G, Sane R, Zhou J. Templeton I, et al. Among authors: sane r. Methods Mol Biol. 2021;2342:695-707. doi: 10.1007/978-1-0716-1554-6_25. Methods Mol Biol. 2021. PMID: 34272713

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

96 results

Search Page

Filters