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107 results

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Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.
Yu LM, Bafadhel M, Dorward J, Hayward G, Saville BR, Gbinigie O, Van Hecke O, Ogburn E, Evans PH, Thomas NPB, Patel MG, Richards D, Berry N, Detry MA, Saunders C, Fitzgerald M, Harris V, Shanyinde M, de Lusignan S, Andersson MI, Barnes PJ, Russell REK, Nicolau DV Jr, Ramakrishnan S, Hobbs FDR, Butler CC; PRINCIPLE Trial Collaborative Group. Yu LM, et al. Among authors: saville br. Lancet. 2021 Sep 4;398(10303):843-855. doi: 10.1016/S0140-6736(21)01744-X. Epub 2021 Aug 10. Lancet. 2021. PMID: 34388395 Free PMC article. Clinical Trial.
Decision curve analysis.
Fitzgerald M, Saville BR, Lewis RJ. Fitzgerald M, et al. Among authors: saville br. JAMA. 2015 Jan 27;313(4):409-10. doi: 10.1001/jama.2015.37. JAMA. 2015. PMID: 25626037 No abstract available.
A trial like ALIC4E: why design a platform, response-adaptive, open, randomised controlled trial of antivirals for influenza-like illness?
Butler CC, Coenen S, Saville BR, Cook J, van der Velden A, Homes J, de Jong M, Little P, Goossens H, Beutels P, Ieven M, Francis N, Moons P, Bongard E, Verheij T. Butler CC, et al. Among authors: saville br. ERJ Open Res. 2018 May 8;4(2):00046-2018. doi: 10.1183/23120541.00046-2018. eCollection 2018 Apr. ERJ Open Res. 2018. PMID: 29761108 Free PMC article.
Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial.
Butler CC, van der Velden AW, Bongard E, Saville BR, Holmes J, Coenen S, Cook J, Francis NA, Lewis RJ, Godycki-Cwirko M, Llor C, Chlabicz S, Lionis C, Seifert B, Sundvall PD, Colliers A, Aabenhus R, Bjerrum L, Jonassen Harbin N, Lindbæk M, Glinz D, Bucher HC, Kovács B, Radzeviciene Jurgute R, Touboul Lundgren P, Little P, Murphy AW, De Sutter A, Openshaw P, de Jong MD, Connor JT, Matheeussen V, Ieven M, Goossens H, Verheij TJ. Butler CC, et al. Among authors: saville br. Lancet. 2020 Jan 4;395(10217):42-52. doi: 10.1016/S0140-6736(19)32982-4. Epub 2019 Dec 12. Lancet. 2020. PMID: 31839279 Clinical Trial.
Oseltamivir for coronavirus illness: post-hoc exploratory analysis of an open-label, pragmatic, randomised controlled trial in European primary care from 2016 to 2018.
Coenen S, van der Velden AW, Cianci D, Goossens H, Bongard E, Saville BR, Gobat N, de Paor M, Ieven M, Verheij TJ, Butler CC. Coenen S, et al. Among authors: saville br. Br J Gen Pract. 2020 Jun 25;70(696):e444-e449. doi: 10.3399/bjgp20X711941. Print 2020 Jul. Br J Gen Pract. 2020. PMID: 32571773 Free PMC article. Clinical Trial.
Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE): protocol for a randomised, controlled, open-label, adaptive platform, trial of community treatment of COVID-19 syndromic illness in people at higher risk.
Hayward G, Butler CC, Yu LM, Saville BR, Berry N, Dorward J, Gbinigie O, van Hecke O, Ogburn E, Swayze H, Bongard E, Allen J, Tonner S, Rutter H, Tonkin-Crine S, Borek A, Judge D, Grabey J, de Lusignan S, Thomas NPB, Evans PH, Andersson MI, Llewelyn M, Patel M, Hopkins S, Hobbs FDR. Hayward G, et al. Among authors: saville br. BMJ Open. 2021 Jun 18;11(6):e046799. doi: 10.1136/bmjopen-2020-046799. BMJ Open. 2021. PMID: 34145016 Free PMC article.
Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.
Butler CC, Yu LM, Dorward J, Gbinigie O, Hayward G, Saville BR, Van Hecke O, Berry N, Detry MA, Saunders C, Fitzgerald M, Harris V, Djukanovic R, Gadola S, Kirkpatrick J, de Lusignan S, Ogburn E, Evans PH, Thomas NPB, Patel MG, Hobbs FDR; PRINCIPLE Trial Collaborative Group. Butler CC, et al. Among authors: saville br. Lancet Respir Med. 2021 Sep;9(9):1010-1020. doi: 10.1016/S2213-2600(21)00310-6. Epub 2021 Jul 27. Lancet Respir Med. 2021. PMID: 34329624 Free PMC article. Clinical Trial.
107 results