Li D - Search Results

1

Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods.

Yuan T, Yan N, Fei T, Zheng J, Meng J, Li N, Liu J, Zhang H, Xie L, Ying W, Li D, Shi L, Sun Y, Li Y, Li Y, Sun Y, Zuo E. Yuan T, et al. Among authors: li d, li y, li n. Nat Commun. 2021 Aug 12;12(1):4902. doi: 10.1038/s41467-021-25217-y. Nat Commun. 2021. PMID: 34385461 Free PMC article.

2

ZPAC is required for normal spermatogenesis in mice.

Zuo EW, Yang XG, Lu YQ, Xie L, Shang JH, Li D, Yang H, Hu LL, Zhao HM, Lu SS, Lu KH. Zuo EW, et al. Among authors: li d. Mol Reprod Dev. 2015 Oct;82(10):747-55. doi: 10.1002/mrd.22507. Epub 2015 Jul 6. Mol Reprod Dev. 2015. PMID: 26153379

3

Gene editing in a Myo6 semi-dominant mouse model rescues auditory function.

Xue Y, Hu X, Wang D, Li D, Li Y, Wang F, Huang M, Gu X, Xu Z, Zhou J, Wang J, Chai R, Shen J, Chen ZY, Li GL, Yang H, Li H, Zuo E, Shu Y. Xue Y, et al. Among authors: li d, li y, li h, li gl. Mol Ther. 2022 Jan 5;30(1):105-118. doi: 10.1016/j.ymthe.2021.06.015. Epub 2021 Jun 24. Mol Ther. 2022. PMID: 34174443 Free PMC article.

4

Treatment of autosomal recessive hearing loss via in vivo CRISPR/Cas9-mediated optimized homology-directed repair in mice.

Gu X, Hu X, Wang D, Xu Z, Wang F, Li D, Li GL, Yang H, Li H, Zuo E, Shu Y. Gu X, et al. Among authors: li d, li h, li gl. Cell Res. 2022 Jul;32(7):699-702. doi: 10.1038/s41422-022-00624-y. Epub 2022 Feb 23. Cell Res. 2022. PMID: 35197607 Free PMC article. No abstract available.

5

Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos.

Wei Y, Li Z, Xu K, Feng H, Xie L, Li D, Zuo Z, Zhang M, Xu C, Yang H, Zuo E. Wei Y, et al. Among authors: li d, li z. Cell Discov. 2022 Mar 18;8(1):27. doi: 10.1038/s41421-022-00391-5. Cell Discov. 2022. PMID: 35304438 Free PMC article. No abstract available.

6

Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes.

Yuan T, Wu L, Li S, Zheng J, Li N, Xiao X, Zhang H, Fei T, Xie L, Zuo Z, Li D, Huang P, Feng H, Cao Y, Yan N, Wei X, Shi L, Sun Y, Wei W, Sun Y, Zuo E. Yuan T, et al. Among authors: li s, li d, li n. Cell Discov. 2024 Feb 20;10(1):20. doi: 10.1038/s41421-023-00624-1. Cell Discov. 2024. PMID: 38378648 Free PMC article.

7

FokI-RYdCas9 Mediates Nearly PAM-Less and High-Precise Gene Editing in Human Cells.

Li D, Cao Y, Xie L, He C, Jiao D, Ma M, Zuo Z, Zuo E, Yang X. Li D, et al. Curr Issues Mol Biol. 2024 Apr 27;46(5):4021-4034. doi: 10.3390/cimb46050248. Curr Issues Mol Biol. 2024. PMID: 38785516 Free PMC article.

8

Reducing off-target effects of DdCBEs by reversing amino acid charge near DNA interaction sites.

Xie L, Cao Y, Li D, Ma M, Jiao D, Feng H, Zuo Z, Zuo E. Xie L, et al. Among authors: li d. Cell Res. 2024 Sep 10. doi: 10.1038/s41422-024-01028-w. Online ahead of print. Cell Res. 2024. PMID: 39256612 No abstract available.

9

CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression.

Han Y, Tan X, Jin T, Zhao S, Hu L, Zhang W, Kurita R, Nakamura Y, Liu J, Li D, Zhang Z, Fang X, Huang S. Han Y, et al. Among authors: li d. Eur J Pharmacol. 2022 Mar 5;918:174788. doi: 10.1016/j.ejphar.2022.174788. Epub 2022 Jan 28. Eur J Pharmacol. 2022. PMID: 35093321

10

A novel long noncoding RNA, AC092834.1, regulates the adipogenic differentiation of human adipose-derived mesenchymal stem cells via the DKK1/Wnt/β-catenin signaling pathway.

Fan L, Xu H, Li D, Li H, Lu D. Fan L, et al. Among authors: li d, li h. Biochem Biophys Res Commun. 2020 May 7;525(3):747-754. doi: 10.1016/j.bbrc.2020.02.140. Epub 2020 Mar 4. Biochem Biophys Res Commun. 2020. PMID: 32145912

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