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Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer.
Hong S, Klein EA, Das Gupta J, Hanke K, Weight CJ, Nguyen C, Gaughan C, Kim KA, Bannert N, Kirchhoff F, Munch J, Silverman RH. Hong S, et al. Among authors: gaughan c. J Virol. 2009 Jul;83(14):6995-7003. doi: 10.1128/JVI.00268-09. Epub 2009 Apr 29. J Virol. 2009. PMID: 19403677 Free PMC article.
Infection, viral dissemination, and antibody responses of rhesus macaques exposed to the human gammaretrovirus XMRV.
Onlamoon N, Das Gupta J, Sharma P, Rogers K, Suppiah S, Rhea J, Molinaro RJ, Gaughan C, Dong B, Klein EA, Qiu X, Devare S, Schochetman G, Hackett J Jr, Silverman RH, Villinger F. Onlamoon N, et al. Among authors: gaughan c. J Virol. 2011 May;85(9):4547-57. doi: 10.1128/JVI.02411-10. Epub 2011 Feb 16. J Virol. 2011. PMID: 21325416 Free PMC article.
RNase L triggers autophagy in response to viral infections.
Chakrabarti A, Ghosh PK, Banerjee S, Gaughan C, Silverman RH. Chakrabarti A, et al. Among authors: gaughan c. J Virol. 2012 Oct;86(20):11311-21. doi: 10.1128/JVI.00270-12. Epub 2012 Aug 8. J Virol. 2012. PMID: 22875977 Free PMC article.
Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Huang H, Zeqiraj E, Dong B, Jha BK, Duffy NM, Orlicky S, Thevakumaran N, Talukdar M, Pillon MC, Ceccarelli DF, Wan LC, Juang YC, Mao DY, Gaughan C, Brinton MA, Perelygin AA, Kourinov I, Guarné A, Silverman RH, Sicheri F. Huang H, et al. Among authors: gaughan c. Mol Cell. 2014 Jan 23;53(2):221-34. doi: 10.1016/j.molcel.2013.12.025. Mol Cell. 2014. PMID: 24462203 Free PMC article.
RNase L is a negative regulator of cell migration.
Banerjee S, Li G, Li Y, Gaughan C, Baskar D, Parker Y, Lindner DJ, Weiss SR, Silverman RH. Banerjee S, et al. Among authors: gaughan c. Oncotarget. 2015 Dec 29;6(42):44360-72. doi: 10.18632/oncotarget.6246. Oncotarget. 2015. PMID: 26517238 Free PMC article.
74 results