Jackson SE - Search Results

1

Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation.

Orozco CT, Edgeworth MJ, Devine PWA, Hines AR, Cornwell O, Thompson C, Wang X, Phillips JJ, Ravn P, Jackson SE, Bond NJ. Orozco CT, et al. Among authors: jackson se. Bioconjug Chem. 2021 Aug 18;32(8):1834-1844. doi: 10.1021/acs.bioconjchem.1c00286. Epub 2021 Aug 9. Bioconjug Chem. 2021. PMID: 34369158 Free article.

2

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs.

Phillips JJ, Yao ZP, Zhang W, McLaughlin S, Laue ED, Robinson CV, Jackson SE. Phillips JJ, et al. Among authors: jackson se. J Mol Biol. 2007 Oct 5;372(5):1189-203. doi: 10.1016/j.jmb.2007.04.059. Epub 2007 Apr 27. J Mol Biol. 2007. PMID: 17764690

3

Mechanistic insights into the rational design of masked antibodies.

Orozco CT, Bersellini M, Irving LM, Howard WW, Hargreaves D, Devine PWA, Siouve E, Browne GJ, Bond NJ, Phillips JJ, Ravn P, Jackson SE. Orozco CT, et al. Among authors: jackson se. MAbs. 2022 Jan-Dec;14(1):2095701. doi: 10.1080/19420862.2022.2095701. MAbs. 2022. PMID: 35799328 Free PMC article.

4

All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading.

Dannheim FM, Walsh SJ, Orozco CT, Hansen AH, Bargh JD, Jackson SE, Bond NJ, Parker JS, Carroll JS, Spring DR. Dannheim FM, et al. Among authors: jackson se. Chem Sci. 2022 Jul 20;13(30):8781-8790. doi: 10.1039/d2sc02198f. eCollection 2022 Aug 4. Chem Sci. 2022. PMID: 35975158 Free PMC article.

5

De novo design of knotted tandem repeat proteins.

Doyle LA, Takushi B, Kibler RD, Milles LF, Orozco CT, Jones JD, Jackson SE, Stoddard BL, Bradley P. Doyle LA, et al. Among authors: jackson se. Nat Commun. 2023 Oct 24;14(1):6746. doi: 10.1038/s41467-023-42388-y. Nat Commun. 2023. PMID: 37875492 Free PMC article.

6

The folding pathway of ubiquitin from all-atom molecular dynamics simulations.

Marianayagam NJ, Jackson SE. Marianayagam NJ, et al. Among authors: jackson se. Biophys Chem. 2004 Oct 1;111(2):159-71. doi: 10.1016/j.bpc.2004.05.009. Biophys Chem. 2004. PMID: 15381313

7

A recurring theme in protein engineering: the design, stability and folding of repeat proteins.

Main ER, Lowe AR, Mochrie SG, Jackson SE, Regan L. Main ER, et al. Among authors: jackson se. Curr Opin Struct Biol. 2005 Aug;15(4):464-71. doi: 10.1016/j.sbi.2005.07.003. Curr Opin Struct Biol. 2005. PMID: 16043339 Review.

8

Native-state dynamics of the ubiquitin family: implications for function and evolution.

Marianayagam NJ, Jackson SE. Marianayagam NJ, et al. Among authors: jackson se. J R Soc Interface. 2005 Mar 22;2(2):47-54. doi: 10.1098/rsif.2004.0025. J R Soc Interface. 2005. PMID: 16849163 Free PMC article.

9

The folding, stability and conformational dynamics of beta-barrel fluorescent proteins.

Hsu ST, Blaser G, Jackson SE. Hsu ST, et al. Among authors: jackson se. Chem Soc Rev. 2009 Oct;38(10):2951-65. doi: 10.1039/b908170b. Epub 2009 Sep 4. Chem Soc Rev. 2009. PMID: 19771338 Review.

10

Ubiquitin: a small protein folding paradigm.

Jackson SE. Jackson SE. Org Biomol Chem. 2006 May 21;4(10):1845-53. doi: 10.1039/b600829c. Epub 2006 Apr 27. Org Biomol Chem. 2006. PMID: 16688326 Review.

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