Chen SH - Search Results

1

ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.

Zhao F, Kim W, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J. Zhao F, et al. Among authors: chen sh, chen y. Nat Cell Biol. 2021 Aug;23(8):894-904. doi: 10.1038/s41556-021-00723-9. Epub 2021 Aug 5. Nat Cell Biol. 2021. PMID: 34354233

2

NADP⁺ is an endogenous PARP inhibitor in DNA damage response and tumor suppression.

Bian C, Zhang C, Luo T, Vyas A, Chen SH, Liu C, Kassab MA, Yang Y, Kong M, Yu X. Bian C, et al. Among authors: chen sh. Nat Commun. 2019 Feb 11;10(1):693. doi: 10.1038/s41467-019-08530-5. Nat Commun. 2019. PMID: 30741937 Free PMC article.

3

Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors.

Yang G, Liu C, Chen SH, Kassab MA, Hoff JD, Walter NG, Yu X. Yang G, et al. Among authors: chen sh. Nucleic Acids Res. 2018 Apr 20;46(7):3446-3457. doi: 10.1093/nar/gky088. Nucleic Acids Res. 2018. PMID: 29447383 Free PMC article.

4

Human DNA ligase IV is able to use NAD+ as an alternative adenylation donor for DNA ends ligation.

Chen SH, Yu X. Chen SH, et al. Nucleic Acids Res. 2019 Feb 20;47(3):1321-1334. doi: 10.1093/nar/gky1202. Nucleic Acids Res. 2019. PMID: 30496552 Free PMC article.

5

Poly(ADP-ribosyl)ation mediates early phase histone eviction at DNA lesions.

Yang G, Chen Y, Wu J, Chen SH, Liu X, Singh AK, Yu X. Yang G, et al. Among authors: chen sh, chen y. Nucleic Acids Res. 2020 Apr 6;48(6):3001-3013. doi: 10.1093/nar/gkaa022. Nucleic Acids Res. 2020. PMID: 31965183 Free PMC article.

6

Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis.

Chen Q, Ma K, Liu X, Chen SH, Li P, Yu Y, Leung AKL, Yu X. Chen Q, et al. Among authors: chen sh. Cell Discov. 2022 Jan 18;8(1):3. doi: 10.1038/s41421-021-00355-1. Cell Discov. 2022. PMID: 35039483 Free PMC article.

7

Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies.

Chen SH, Yu X. Chen SH, et al. Sci Adv. 2019 Apr 10;5(4):eaav4340. doi: 10.1126/sciadv.aav4340. eCollection 2019 Apr. Sci Adv. 2019. PMID: 30989114 Free PMC article.

8

AI26 inhibits the ADP-ribosylhydrolase ARH3 and suppresses DNA damage repair.

Liu X, Xie R, Yu LL, Chen SH, Yang X, Singh AK, Li H, Wu C, Yu X. Liu X, et al. Among authors: chen sh. J Biol Chem. 2020 Oct 2;295(40):13838-13849. doi: 10.1074/jbc.RA120.012801. Epub 2020 Aug 4. J Biol Chem. 2020. PMID: 32753484 Free PMC article.

9

Poly-ADP ribosylation in DNA damage response and cancer therapy.

Hou WH, Chen SH, Yu X. Hou WH, et al. Among authors: chen sh. Mutat Res Rev Mutat Res. 2019 Apr-Jun;780:82-91. doi: 10.1016/j.mrrev.2017.09.004. Epub 2017 Sep 20. Mutat Res Rev Mutat Res. 2019. PMID: 31395352 Free PMC article. Review.

10

The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response.

Zhang F, Shi J, Chen SH, Bian C, Yu X. Zhang F, et al. Among authors: chen sh. Nucleic Acids Res. 2015 Dec 15;43(22):10782-94. doi: 10.1093/nar/gkv939. Epub 2015 Sep 22. Nucleic Acids Res. 2015. PMID: 26400172 Free PMC article.

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