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METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation.
Orellana EA, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, Lim J, Aspris D, Sendinc E, Garyfallos DA, Gu M, Ali R, Gutierrez A, Mikutis S, Bernardes GJL, Fischer ES, Bradley A, Vassiliou GS, Slack FJ, Tzelepis K, Gregory RI. Orellana EA, et al. Among authors: gutierrez a. Mol Cell. 2021 Aug 19;81(16):3323-3338.e14. doi: 10.1016/j.molcel.2021.06.031. Epub 2021 Aug 4. Mol Cell. 2021. PMID: 34352207 Free PMC article.
Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias.
Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Stevenson KE, Neuberg DS, Orellana E, Stanulla M, Gregory RI, Bauer DE, Wagner FF, Stegmaier K, Gutierrez A. Hinze L, et al. Among authors: gutierrez a. Cancer Cell. 2019 Apr 15;35(4):664-676.e7. doi: 10.1016/j.ccell.2019.03.004. Cancer Cell. 2019. PMID: 30991026 Free PMC article.
T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.
Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, Look AT. Feng H, et al. Among authors: gutierrez a. Cancer Cell. 2010 Oct 19;18(4):353-66. doi: 10.1016/j.ccr.2010.09.009. Cancer Cell. 2010. PMID: 20951945 Free PMC article.
Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia.
Burns MA, Liao ZW, Yamagata N, Pouliot GP, Stevenson KE, Neuberg DS, Thorner AR, Ducar M, Silverman EA, Hunger SP, Loh ML, Winter SS, Dunsmore KP, Wood B, Devidas M, Harris MH, Silverman LB, Sallan SE, Gutierrez A. Burns MA, et al. Among authors: gutierrez a. Leukemia. 2018 Oct;32(10):2126-2137. doi: 10.1038/s41375-018-0097-x. Epub 2018 Mar 20. Leukemia. 2018. PMID: 29654263 Free PMC article.
Leukemia propagating cells Akt up.
Gutierrez A, Roderick JE, Kelliher MA. Gutierrez A, et al. Cancer Cell. 2014 Mar 17;25(3):263-5. doi: 10.1016/j.ccr.2014.02.022. Cancer Cell. 2014. PMID: 24651006 Free article.
Thymocyte transformation enhanced.
Pouliot GP, Gutierrez A. Pouliot GP, et al. Among authors: gutierrez a. Nat Med. 2014 Oct;20(10):1096-7. doi: 10.1038/nm.3711. Nat Med. 2014. PMID: 25295936 No abstract available.
NOTCH and PI3K-AKT pathways intertwined.
Gutierrez A, Look AT. Gutierrez A, et al. Cancer Cell. 2007 Nov;12(5):411-3. doi: 10.1016/j.ccr.2007.10.027. Cancer Cell. 2007. PMID: 17996644 Free article.
SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W. Inuzuka H, et al. Among authors: gutierrez a. Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732. Nature. 2011. PMID: 21368833 Free PMC article.
Supramolecular assembly of GSK3α as a cellular response to amino acid starvation.
Hinze L, Schreek S, Zeug A, Ibrahim NK, Fehlhaber B, Loxha L, Cinar B, Ponimaskin E, Degar J, McGuckin C, Chiosis G, Eckert C, Cario G, Bornhauser B, Bourquin JP, Stanulla M, Gutierrez A. Hinze L, et al. Among authors: gutierrez a. Mol Cell. 2022 Aug 4;82(15):2858-2870.e8. doi: 10.1016/j.molcel.2022.05.025. Epub 2022 Jun 21. Mol Cell. 2022. PMID: 35732190 Free PMC article.
2,855 results