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Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention.
Summers RL, Pasaje CFA, Pisco JP, Striepen J, Luth MR, Kumpornsin K, Carpenter EF, Munro JT, Lin D, Plater A, Punekar AS, Shepherd AM, Shepherd SM, Vanaerschot M, Murithi JM, Rubiano K, Akidil A, Ottilie S, Mittal N, Dilmore AH, Won M, Mandt REK, McGowen K, Owen E, Walpole C, Llinás M, Lee MCS, Winzeler EA, Fidock DA, Gilbert IH, Wirth DF, Niles JC, Baragaña B, Lukens AK. Summers RL, et al. Among authors: mandt rek. Cell Chem Biol. 2022 Feb 17;29(2):191-201.e8. doi: 10.1016/j.chembiol.2021.07.010. Epub 2021 Aug 3. Cell Chem Biol. 2022. PMID: 34348113 Free PMC article.
Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow.
De Niz M, Meibalan E, Mejia P, Ma S, Brancucci NMB, Agop-Nersesian C, Mandt R, Ngotho P, Hughes KR, Waters AP, Huttenhower C, Mitchell JR, Martinelli R, Frischknecht F, Seydel KB, Taylor T, Milner D, Heussler VT, Marti M. De Niz M, et al. Sci Adv. 2018 May 23;4(5):eaat3775. doi: 10.1126/sciadv.aat3775. eCollection 2018 May. Sci Adv. 2018. PMID: 29806032 Free PMC article.
Resistance to Second-Generation HIV-1 Maturation Inhibitors.
Urano E, Timilsina U, Kaplan JA, Ablan S, Ghimire D, Pham P, Kuruppu N, Mandt R, Durell SR, Nitz TJ, Martin DE, Wild CT, Gaur R, Freed EO. Urano E, et al. J Virol. 2019 Mar 5;93(6):e02017-18. doi: 10.1128/JVI.02017-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30567982 Free PMC article.