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Immortalized striatal precursor neurons from Huntington's disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics.
Akimov SS, Jiang M, Kedaigle AJ, Arbez N, Marque LO, Eddings CR, Ranum PT, Whelan E, Tang A, Wang R, DeVine LR, Talbot CC, Cole RN, Ratovitski T, Davidson BL, Fraenkel E, Ross CA. Akimov SS, et al. Among authors: wang r. Hum Mol Genet. 2021 Nov 30;30(24):2469-2487. doi: 10.1093/hmg/ddab200. Hum Mol Genet. 2021. PMID: 34296279 Free PMC article.
Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
Jiang M, Zhang X, Liu H, LeBron J, Alexandris A, Peng Q, Gu H, Yang F, Li Y, Wang R, Hou Z, Arbez N, Ren Q, Dong JL, Whela E, Wang R, Ratovitski T, Troncoso JC, Mori S, Ross CA, Lim J, Duan W. Jiang M, et al. Among authors: wang r. Hum Mol Genet. 2020 May 28;29(8):1340-1352. doi: 10.1093/hmg/ddaa061. Hum Mol Genet. 2020. PMID: 32242231 Free PMC article.
Perfusion-Based Relative Cerebral Blood Volume Is Associated With Functional Dependence in Large-Vessel Occlusion Ischemic Stroke.
Lakhani DA, Balar AB, Koneru M, Wen S, Ozkara BB, Caplan J, Dmytriw AA, Wang R, Lu H, Hoseinyazdi M, Nabi M, Mazumdar I, Cho A, Chen K, Sepehri S, Hyson N, Xu R, Urrutia V, Luna LP, Hillis A, Heit JJ, Albers GW, Rai AT, Faizy T, Wintermark M, Nael K, Yedavalli VS. Lakhani DA, et al. Among authors: wang r. J Am Heart Assoc. 2024 Nov 22:e034242. doi: 10.1161/JAHA.124.034242. Online ahead of print. J Am Heart Assoc. 2024. PMID: 39575711
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