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Reactivation of a developmentally silenced embryonic globin gene.
Nat Commun. 2021 Jul 21;12(1):4439. doi: 10.1038/s41467-021-24402-3.
Nat Commun. 2021.
PMID: 34290235
Free PMC article.
A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker.
Bozhilov YK, Downes DJ, Telenius J, Marieke Oudelaar A, Olivier EN, Mountford JC, Hughes JR, Gibbons RJ, Higgs DR.
Bozhilov YK, et al. Among authors: marieke oudelaar a.
Nat Commun. 2021 Jun 21;12(1):3806. doi: 10.1038/s41467-021-23980-6.
Nat Commun. 2021.
PMID: 34155213
Free PMC article.
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Genetic dissection of the α-globin super-enhancer in vivo.
Hay D, Hughes JR, Babbs C, Davies JOJ, Graham BJ, Hanssen L, Kassouf MT, Marieke Oudelaar AM, Sharpe JA, Suciu MC, Telenius J, Williams R, Rode C, Li PS, Pennacchio LA, Sloane-Stanley JA, Ayyub H, Butler S, Sauka-Spengler T, Gibbons RJ, Smith AJH, Wood WG, Higgs DR.
Hay D, et al. Among authors: marieke oudelaar am.
Nat Genet. 2016 Aug;48(8):895-903. doi: 10.1038/ng.3605. Epub 2016 Jul 4.
Nat Genet. 2016.
PMID: 27376235
Free PMC article.
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