Ganesh T - Search Results

1

Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival.

De La Cruz JA, Ganesh T, Diebold BA, Cao W, Hofstetter A, Singh N, Kumar A, McCoy J, Ranjan P, Smith SME, Sambhara S, Lambeth JD, Gangappa S. De La Cruz JA, et al. Among authors: ganesh t. PLoS One. 2021 Jul 19;16(7):e0254632. doi: 10.1371/journal.pone.0254632. eCollection 2021. PLoS One. 2021. PMID: 34280220 Free PMC article.

2

Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits.

Smith SM, Min J, Ganesh T, Diebold B, Kawahara T, Zhu Y, McCoy J, Sun A, Snyder JP, Fu H, Du Y, Lewis I, Lambeth JD. Smith SM, et al. Among authors: ganesh t. Chem Biol. 2012 Jun 22;19(6):752-63. doi: 10.1016/j.chembiol.2012.04.015. Chem Biol. 2012. PMID: 22726689 Free PMC article.

3

High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases.

Zielonka J, Cheng G, Zielonka M, Ganesh T, Sun A, Joseph J, Michalski R, O'Brien WJ, Lambeth JD, Kalyanaraman B. Zielonka J, et al. Among authors: ganesh t. J Biol Chem. 2014 Jun 6;289(23):16176-89. doi: 10.1074/jbc.M114.548693. Epub 2014 Apr 24. J Biol Chem. 2014. PMID: 24764302 Free PMC article.

4

Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase.

Li Y, Ganesh T, Diebold BA, Zhu Y, McCoy JW, Smith SM, Sun A, Lambeth JD. Li Y, et al. Among authors: ganesh t. ACS Med Chem Lett. 2015 Aug 31;6(10):1047-52. doi: 10.1021/acsmedchemlett.5b00287. eCollection 2015 Oct 8. ACS Med Chem Lett. 2015. PMID: 26487910 Free PMC article.

5

Cyclooxygenase-2 in epilepsy.

Rojas A, Jiang J, Ganesh T, Yang MS, Lelutiu N, Gueorguieva P, Dingledine R. Rojas A, et al. Among authors: ganesh t. Epilepsia. 2014 Jan;55(1):17-25. doi: 10.1111/epi.12461. Epub 2013 Nov 8. Epilepsia. 2014. PMID: 24446952 Free PMC article. Review.

6

An Agonist Dependent Allosteric Antagonist of Prostaglandin EP2 Receptors.

Jiang C, Amaradhi R, Ganesh T, Dingledine R. Jiang C, et al. Among authors: ganesh t. ACS Chem Neurosci. 2020 May 20;11(10):1436-1446. doi: 10.1021/acschemneuro.0c00078. Epub 2020 May 6. ACS Chem Neurosci. 2020. PMID: 32324375

7

EP2 Receptor Signaling Regulates Microglia Death.

Fu Y, Yang MS, Jiang J, Ganesh T, Joe E, Dingledine R. Fu Y, et al. Among authors: ganesh t. Mol Pharmacol. 2015 Jul;88(1):161-70. doi: 10.1124/mol.115.098202. Epub 2015 Feb 25. Mol Pharmacol. 2015. PMID: 25715797 Free PMC article.

8

Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties.

Ganesh T, Banik A, Dingledine R, Wang W, Amaradhi R. Ganesh T, et al. Mol Pharm. 2018 Dec 3;15(12):5809-5817. doi: 10.1021/acs.molpharmaceut.8b00764. Epub 2018 Nov 15. Mol Pharm. 2018. PMID: 30398879 Free PMC article.

9

The COX-2/prostanoid signaling cascades in seizure disorders.

Rojas A, Chen D, Ganesh T, Varvel NH, Dingledine R. Rojas A, et al. Among authors: ganesh t. Expert Opin Ther Targets. 2019 Jan;23(1):1-13. doi: 10.1080/14728222.2019.1554056. Epub 2018 Dec 2. Expert Opin Ther Targets. 2019. PMID: 30484341 Free PMC article. Review.

10

Novel Microglia Cell Line Expressing the Human EP2 Receptor.

Rojas A, Banik A, Chen D, Flood K, Ganesh T, Dingledine R. Rojas A, et al. Among authors: ganesh t. ACS Chem Neurosci. 2019 Oct 16;10(10):4280-4292. doi: 10.1021/acschemneuro.9b00311. Epub 2019 Sep 11. ACS Chem Neurosci. 2019. PMID: 31469538

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