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Page 1
The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Klein BJ, Deshpande A, Cox KL, Xuan F, Zandian M, Barbosa K, Khanal S, Tong Q, Zhang Y, Zhang P, Sinha A, Bohlander SK, Shi X, Wen H, Poirier MG, Deshpande AJ, Kutateladze TG. Klein BJ, et al. Among authors: deshpande a, deshpande aj. Nat Commun. 2021 Jul 5;12(1):4130. doi: 10.1038/s41467-021-24418-9. Nat Commun. 2021. PMID: 34226546 Free PMC article.
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.
Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Deshpande AJ, et al. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. Cancer Cell. 2006. PMID: 17097559 Free article.
Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia.
Rawat VP, Thoene S, Naidu VM, Arseni N, Heilmeier B, Metzeler K, Petropoulos K, Deshpande A, Quintanilla-Martinez L, Bohlander SK, Spiekermann K, Hiddemann W, Feuring-Buske M, Buske C. Rawat VP, et al. Blood. 2008 Jan 1;111(1):309-19. doi: 10.1182/blood-2007-04-085407. Epub 2007 Sep 12. Blood. 2008. PMID: 17855634 Free article.
The CALM and CALM/AF10 interactor CATS is a marker for proliferation.
Archangelo LF, Greif PA, Hölzel M, Harasim T, Kremmer E, Przemeck GK, Eick D, Deshpande AJ, Buske C, de Angelis MH, Saad ST, Bohlander SK. Archangelo LF, et al. Among authors: deshpande aj. Mol Oncol. 2008 Dec;2(4):356-67. doi: 10.1016/j.molonc.2008.08.001. Epub 2008 Sep 4. Mol Oncol. 2008. PMID: 19383357 Free PMC article.
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. Deshpande AJ, et al. Among authors: deshpande a. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. Cancer Cell. 2014. PMID: 25464900 Free PMC article.
65 results