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Haemodynamic-directed cardiopulmonary resuscitation promotes mitochondrial fusion and preservation of mitochondrial mass after successful resuscitation in a pediatric porcine model.
Senthil K, Morgan RW, Hefti MM, Karlsson M, Lautz AJ, Mavroudis CD, Ko T, Nadkarni VM, Ehinger J, Berg RA, Sutton RM, McGowan FX, Kilbaugh TJ. Senthil K, et al. Among authors: hefti mm. Resusc Plus. 2021 Apr 29;6:100124. doi: 10.1016/j.resplu.2021.100124. eCollection 2021 Jun. Resusc Plus. 2021. PMID: 34223382 Free PMC article.
Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine.
Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ. Mavroudis CD, et al. Eur J Cardiothorac Surg. 2018 Jul 1;54(1):162-168. doi: 10.1093/ejcts/ezx467. Eur J Cardiothorac Surg. 2018. PMID: 29346537 Free PMC article.
Oxygen Exposure During Cardiopulmonary Resuscitation Is Associated With Cerebral Oxidative Injury in a Randomized, Blinded, Controlled, Preclinical Trial.
Marquez AM, Morgan RW, Ko T, Landis WP, Hefti MM, Mavroudis CD, McManus MJ, Karlsson M, Starr J, Roberts AL, Lin Y, Nadkarni V, Licht DJ, Berg RA, Sutton RM, Kilbaugh TJ. Marquez AM, et al. Among authors: hefti mm. J Am Heart Assoc. 2020 May 5;9(9):e015032. doi: 10.1161/JAHA.119.015032. Epub 2020 Apr 23. J Am Heart Assoc. 2020. PMID: 32321350 Free PMC article.
Increased cerebral mitochondrial dysfunction and reactive oxygen species with cardiopulmonary bypass.
Volk LE, Mavroudis CD, Ko T, Hallowell T, Delso N, Roberts AL, Starr J, Landis W, Lin Y, Hefti M, Morgan RW, Melchior RW, Rosenthal TM, Chappell A, Fisher D, Dreher M, Licht DJ, Chen J, Gaynor JW, Mascio CE, Kilbaugh TJ. Volk LE, et al. Eur J Cardiothorac Surg. 2021 Jun 14;59(6):1256-1264. doi: 10.1093/ejcts/ezaa439. Eur J Cardiothorac Surg. 2021. PMID: 33367535 Free PMC article.
A randomized and blinded trial of inhaled nitric oxide in a piglet model of pediatric cardiopulmonary resuscitation.
Morgan RW, Sutton RM, Himebauch AS, Roberts AL, Landis WP, Lin Y, Starr J, Ranganathan A, Delso N, Mavroudis CD, Volk L, Slovis J, Marquez AM, Nadkarni VM, Hefti M, Berg RA, Kilbaugh TJ. Morgan RW, et al. Resuscitation. 2021 May;162:274-283. doi: 10.1016/j.resuscitation.2021.03.004. Epub 2021 Mar 22. Resuscitation. 2021. PMID: 33766668 Free PMC article.
Pediatric Extracorporeal Cardiopulmonary Resuscitation: Development of a Porcine Model and the Influence of Cardiopulmonary Resuscitation Duration on Brain Injury.
Slovis JC, Volk L, Mavroudis C, Hefti M, Landis WP, Roberts AL, Delso N, Hallowell T, Graham K, Starr J, Lin Y, Melchior R, Nadkarni V, Sutton RM, Berg RA, Piel S, Morgan RW, Kilbaugh TJ. Slovis JC, et al. J Am Heart Assoc. 2023 Feb 21;12(4):e026479. doi: 10.1161/JAHA.122.026479. Epub 2023 Feb 15. J Am Heart Assoc. 2023. PMID: 36789866 Free PMC article.
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