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Predictors of Global Non-Motor Symptoms Burden Progression in Parkinson's Disease. Results from the COPPADIS Cohort at 2-Year Follow-Up.
Santos-García D, de Deus T, Cores C, Canfield H, Paz González JM, Martínez Miró C, Valdés Aymerich L, Suárez E, Jesús S, Aguilar M, Pastor P, Planellas L, Cosgaya M, García Caldentey J, Caballol N, Legarda I, Hernández-Vara J, Cabo I, López Manzanares L, González Aramburu I, Ávila Rivera MA, Catalán MJ, Nogueira V, Puente V, Dotor J, Borrué C, Solano B, Álvarez Sauco M, Vela L, Escalante S, Cubo E, Carrillo F, Martínez Castrillo JC, Sánchez Alonso P, Alonso G, López Ariztegui N, Gastón I, Kulisevsky J, Blázquez M, Seijo M, Rúiz Martínez J, Valero C, Kurtis M, de Fábregues O, Ardura J, Alonso R, Ordás C, López Díaz LM, McAfee D, Martinez-Martin P, Mir P, Coppadis Study Group. Santos-García D, et al. Among authors: ordas c. J Pers Med. 2021 Jun 30;11(7):626. doi: 10.3390/jpm11070626. J Pers Med. 2021. PMID: 34209166 Free PMC article.
COPPADIS-2015 (COhort of Patients with PArkinson's DIsease in Spain, 2015), a global--clinical evaluations, serum biomarkers, genetic studies and neuroimaging--prospective, multicenter, non-interventional, long-term study on Parkinson's disease progression.
Santos-García D, Mir P, Cubo E, Vela L, Rodríguez-Oroz MC, Martí MJ, Arbelo JM, Infante J, Kulisevsky J, Martínez-Martín P; COPPADIS Study Group. Santos-García D, et al. BMC Neurol. 2016 Feb 25;16:26. doi: 10.1186/s12883-016-0548-9. BMC Neurol. 2016. PMID: 26911448 Free PMC article.
COPPADIS-2015 (COhort of Patients with PArkinson's DIsease in Spain, 2015): an ongoing global Parkinson's disease project about disease progression with more than 1000 subjects included. Results from the baseline evaluation.
Santos García D, Jesús S, Aguilar M, Planellas LL, García Caldentey J, Caballol N, Legarda I, Hernández Vara J, Cabo I, López Manzanares L, González Aramburu I, Ávila Rivera MA, Catalán MJ, López Díaz L, Puente V, García Moreno JM, Borrué C, Solano Vila B, Álvarez Sauco M, Vela L, Escalante S, Cubo E, Carrillo Padilla F, Martínez Castrillo JC, Sánchez Alonso P, Alonso Losada MG, López Ariztegui N, Gastón I, Kulisevsky J, Menéndez González M, Seijo M, Rúiz Martínez J, Valero C, Kurtis M, de Fábregues-Boixar O, González Ardura J, Prieto Jurczynska C, Martinez-Martin P, Mir P; COPPADIS Study Group. Santos García D, et al. Eur J Neurol. 2019 Nov;26(11):1399-1407. doi: 10.1111/ene.14008. Epub 2019 Jul 4. Eur J Neurol. 2019. PMID: 31179586
Non-motor symptoms burden, mood, and gait problems are the most significant factors contributing to a poor quality of life in non-demented Parkinson's disease patients: Results from the COPPADIS Study Cohort.
Santos García D, de Deus Fonticoba T, Suárez Castro E, Borrué C, Mata M, Solano Vila B, Cots Foraster A, Álvarez Sauco M, Rodríguez Pérez AB, Vela L, Macías Y, Escalante S, Esteve P, Reverté Villarroya S, Cubo E, Casas E, Arnaiz S, Carrillo Padilla F, Pueyo Morlans M, Mir P, Martinez-Martin P; Coppadis Study Group. Santos García D, et al. Parkinsonism Relat Disord. 2019 Sep;66:151-157. doi: 10.1016/j.parkreldis.2019.07.031. Epub 2019 Jul 29. Parkinsonism Relat Disord. 2019. PMID: 31409572
High ultrasensitive serum C-reactive protein may be related to freezing of gait in Parkinson's disease patients.
Santos-García D, de Deus Fonticoba T, Suárez Castro E, Aneiros Díaz A, Paz González JM, Feal Panceiras MJ, García Sancho C, Jesús S, Mir P, Aguilar M, Pastor P, Hernández Vara J, de Fábregues-Boixar O, Puente V, Crespo Cuevas A, González-Aramburu I, Infante J, Carrillo Padilla F, Pueyo M, Escalante S, Bernardo N, Solano B, Cots Foraster A, Martinez-Martin P; COPPADIS Study Group. Santos-García D, et al. J Neural Transm (Vienna). 2019 Dec;126(12):1599-1608. doi: 10.1007/s00702-019-02096-8. Epub 2019 Oct 31. J Neural Transm (Vienna). 2019. PMID: 31673927
Non-motor symptom burden is strongly correlated to motor complications in patients with Parkinson's disease.
Santos-García D, de Deus Fonticoba T, Suárez Castro E, Aneiros Díaz A, McAfee D, Catalán MJ, Alonso-Frech F, Villanueva C, Jesús S, Mir P, Aguilar M, Pastor P, García Caldentey J, Esltelrich Peyret E, Planellas LL, Martí MJ, Caballol N, Hernández Vara J, Martí Andrés G, Cabo I, Ávila Rivera MA, López Manzanares L, Redondo N, Martinez-Martin P; COPPADIS Study Group; McAfee D. Santos-García D, et al. Eur J Neurol. 2020 Jul;27(7):1210-1223. doi: 10.1111/ene.14221. Epub 2020 Apr 24. Eur J Neurol. 2020. PMID: 32181979
The impact of freezing of gait on functional dependency in Parkinson's disease with regard to motor phenotype.
Santos-García D, de Deus-Fonticoba T, Suárez Castro E, M Aneiros Díaz Á, Feal-Painceiras MJ, Paz-González JM, García-Sancho C, Jesús S, Mir P, Planellas L, García-Caldentey J, Caballol N, Legarda I, Hernández-Vara J, González-Aramburu I, Ávila-Rivera MA, Catalán MJ, Nogueira V, Álvarez-Sauco M, Vela L, Escalante S, Cubo E, Sánchez-Alonso P, Alonso-Losada MG, López-Ariztegui N, Martinez-Martin P; COPPADIS Study Group. Santos-García D, et al. Neurol Sci. 2020 Oct;41(10):2883-2892. doi: 10.1007/s10072-020-04404-7. Epub 2020 Apr 24. Neurol Sci. 2020. PMID: 32333181
Non-motor symptom burden in patients with Parkinson's disease with impulse control disorders and compulsive behaviours: results from the COPPADIS cohort.
Jesús S, Labrador-Espinosa MA, Adarmes AD, Méndel-Del Barrio C, Martínez-Castrillo JC, Alonso-Cánovas A, Sánchez Alonso P, Novo-Ponte S, Alonso-Losada MG, López Ariztegui N, Segundo Rodríguez JC, Morales MI, Gastón I, Lacruz Bescos F, Clavero Ibarra P, Kulisevsky J, Pagonabarraga J, Pascual-Sedano B, Martínez-Martín P, Santos-García D, Mir P; COPPADIS Study Group. Jesús S, et al. Sci Rep. 2020 Oct 9;10(1):16893. doi: 10.1038/s41598-020-73756-z. Sci Rep. 2020. PMID: 33037247 Free PMC article.
Falls Predict Acute Hospitalization in Parkinson's Disease.
Santos García D, de Deus Fonticoba T, Cores C, Suárez Castro E, Hernández Vara J, Jesús S, Mir P, Cosgaya M, José Martí M, Pastor P, Cabo I, Seijo M, Legarda I, Vives B, Caballol N, Rúiz Martínez J, Croitoru I, Cubo E, Miranda J, Alonso Losada MG, Labandeira C, López Ariztegui N, Morales-Casado M, González Aramburu I, Infante J, Escalante S, Bernardo N, Blázquez Estrada M, Menéndez González M, García Caldentey J, Borrué C, Vela L, Catalán MJ, Gómez Mayordomo V, Kurtis M, Prieto C, Ordás C, Nogueira V, López Manzanares L, Ávila Rivera MA, Puente V, García Moreno JM, Solano Vila B, Álvarez Sauco M, Carrillo Padilla F, Martínez Castrillo JC, Sánchez Alonso P, Gastón I, Kulisevsky J, Valero C, de Fábregues O, González Ardura J, López Díaz LM, Martinez-Martin P; COPPADIS Study Group. Santos García D, et al. Among authors: ordas c. J Parkinsons Dis. 2023;13(1):105-124. doi: 10.3233/JPD-212539. J Parkinsons Dis. 2023. PMID: 33843696 Free PMC article.
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