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Page 1
Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes.
Wigger L, Barovic M, Brunner AD, Marzetta F, Schöniger E, Mehl F, Kipke N, Friedland D, Burdet F, Kessler C, Lesche M, Thorens B, Bonifacio E, Legido-Quigley C, Barbier Saint Hilaire P, Delerive P, Dahl A, Klose C, Gerl MJ, Simons K, Aust D, Weitz J, Distler M, Schulte AM, Mann M, Ibberson M, Solimena M. Wigger L, et al. Among authors: simons k. Nat Metab. 2021 Jul;3(7):1017-1031. doi: 10.1038/s42255-021-00420-9. Epub 2021 Jun 28. Nat Metab. 2021. PMID: 34183850
Plasma triacylglycerols are biomarkers of β-cell function in mice and humans.
Sánchez-Archidona AR, Cruciani-Guglielmacci C, Roujeau C, Wigger L, Lallement J, Denom J, Barovic M, Kassis N, Mehl F, Weitz J, Distler M, Klose C, Simons K, Ibberson M, Solimena M, Magnan C, Thorens B. Sánchez-Archidona AR, et al. Among authors: simons k. Mol Metab. 2021 Dec;54:101355. doi: 10.1016/j.molmet.2021.101355. Epub 2021 Oct 9. Mol Metab. 2021. PMID: 34634522 Free PMC article.
Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study.
Slieker RC, Donnelly LA, Fitipaldi H, Bouland GA, Giordano GN, Åkerlund M, Gerl MJ, Ahlqvist E, Ali A, Dragan I, Festa A, Hansen MK, Mansour Aly D, Kim M, Kuznetsov D, Mehl F, Klose C, Simons K, Pavo I, Pullen TJ, Suvitaival T, Wretlind A, Rossing P, Lyssenko V, Legido-Quigley C, Groop L, Thorens B, Franks PW, Ibberson M, Rutter GA, Beulens JWJ, 't Hart LM, Pearson ER. Slieker RC, et al. Among authors: simons k. Diabetologia. 2021 Sep;64(9):1982-1989. doi: 10.1007/s00125-021-05490-8. Epub 2021 Jun 10. Diabetologia. 2021. PMID: 34110439 Free PMC article.
Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study.
Slieker RC, Donnelly LA, Fitipaldi H, Bouland GA, Giordano GN, Åkerlund M, Gerl MJ, Ahlqvist E, Ali A, Dragan I, Elders P, Festa A, Hansen MK, van der Heijden AA, Mansour Aly D, Kim M, Kuznetsov D, Mehl F, Klose C, Simons K, Pavo I, Pullen TJ, Suvitaival T, Wretlind A, Rossing P, Lyssenko V, Legido Quigley C, Groop L, Thorens B, Franks PW, Ibberson M, Rutter GA, Beulens JWJ, 't Hart LM, Pearson ER. Slieker RC, et al. Among authors: simons k. Diabetes. 2021 Nov;70(11):2683-2693. doi: 10.2337/db20-1281. Epub 2021 Aug 10. Diabetes. 2021. PMID: 34376475 Free PMC article.
Shotgun Lipidomics Discovered Diurnal Regulation of Lipid Metabolism Linked to Insulin Sensitivity in Nondiabetic Men.
Kessler K, Gerl MJ, Hornemann S, Damm M, Klose C, Petzke KJ, Kemper M, Weber D, Rudovich N, Grune T, Simons K, Kramer A, Pfeiffer AFH, Pivovarova-Ramich O. Kessler K, et al. Among authors: simons k. J Clin Endocrinol Metab. 2020 May 1;105(5):dgz176. doi: 10.1210/clinem/dgz176. J Clin Endocrinol Metab. 2020. PMID: 31680138 Clinical Trial.
Membrane lipidome of an epithelial cell line.
Sampaio JL, Gerl MJ, Klose C, Ejsing CS, Beug H, Simons K, Shevchenko A. Sampaio JL, et al. Among authors: simons k. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1903-7. doi: 10.1073/pnas.1019267108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245337 Free PMC article.
Lipid-dependent protein sorting at the trans-Golgi network.
Surma MA, Klose C, Simons K. Surma MA, et al. Among authors: simons k. Biochim Biophys Acta. 2012 Aug;1821(8):1059-67. doi: 10.1016/j.bbalip.2011.12.008. Epub 2011 Dec 31. Biochim Biophys Acta. 2012. PMID: 22230596 Review.
831 results