McGuirk S - Search Results

1

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer.

McGuirk S, Audet-Delage Y, Annis MG, Xue Y, Vernier M, Zhao K, St-Louis C, Minarrieta L, Patten DA, Morin G, Greenwood CM, Giguère V, Huang S, Siegel PM, St-Pierre J. McGuirk S, et al. Elife. 2021 Jun 28;10:e65150. doi: 10.7554/eLife.65150. Elife. 2021. PMID: 34181531 Free PMC article.

2

PGC-1α promotes the growth of ErbB2/Neu-induced mammary tumors by regulating nutrient supply.

Klimcakova E, Chénard V, McGuirk S, Germain D, Avizonis D, Muller WJ, St-Pierre J. Klimcakova E, et al. Among authors: mcguirk s. Cancer Res. 2012 Mar 15;72(6):1538-46. doi: 10.1158/0008-5472.CAN-11-2967. Epub 2012 Jan 19. Cancer Res. 2012. PMID: 22266114

3

PGC-1α supports glutamine metabolism in breast cancer.

McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J. McGuirk S, et al. Cancer Metab. 2013 Dec 5;1(1):22. doi: 10.1186/2049-3002-1-22. Cancer Metab. 2013. PMID: 24304688 Free PMC article.

4

Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α.

Arnold AS, Gill J, Christe M, Ruiz R, McGuirk S, St-Pierre J, Tabares L, Handschin C. Arnold AS, et al. Among authors: mcguirk s. Nat Commun. 2014 Apr 1;5:3569. doi: 10.1038/ncomms4569. Nat Commun. 2014. PMID: 24686533 Free PMC article.

5

Androgen-Dependent Repression of ERRγ Reprograms Metabolism in Prostate Cancer.

Audet-Walsh É, Yee T, McGuirk S, Vernier M, Ouellet C, St-Pierre J, Giguère V. Audet-Walsh É, et al. Among authors: mcguirk s. Cancer Res. 2017 Jan 15;77(2):378-389. doi: 10.1158/0008-5472.CAN-16-1204. Epub 2016 Nov 7. Cancer Res. 2017. PMID: 27821488

6

mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1.

Morita M, Prudent J, Basu K, Goyon V, Katsumura S, Hulea L, Pearl D, Siddiqui N, Strack S, McGuirk S, St-Pierre J, Larsson O, Topisirovic I, Vali H, McBride HM, Bergeron JJ, Sonenberg N. Morita M, et al. Among authors: mcguirk s. Mol Cell. 2017 Sep 21;67(6):922-935.e5. doi: 10.1016/j.molcel.2017.08.013. Epub 2017 Sep 14. Mol Cell. 2017. PMID: 28918902 Free article.

7

PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs.

Andrzejewski S, Klimcakova E, Johnson RM, Tabariès S, Annis MG, McGuirk S, Northey JJ, Chénard V, Sriram U, Papadopoli DJ, Siegel PM, St-Pierre J. Andrzejewski S, et al. Among authors: mcguirk s. Cell Metab. 2017 Nov 7;26(5):778-787.e5. doi: 10.1016/j.cmet.2017.09.006. Epub 2017 Oct 5. Cell Metab. 2017. PMID: 28988825 Free article.

8

Interplay between ShcA Signaling and PGC-1α Triggers Targetable Metabolic Vulnerabilities in Breast Cancer.

Im YK, Najyb O, Gravel SP, McGuirk S, Ahn R, Avizonis DZ, Chénard V, Sabourin V, Hudson J, Pawson T, Topisirovic I, Pollak M, St-Pierre J, Ursini-Siegel J. Im YK, et al. Among authors: mcguirk s. Cancer Res. 2018 Sep 1;78(17):4826-4838. doi: 10.1158/0008-5472.CAN-17-3696. Epub 2018 Jun 21. Cancer Res. 2018. PMID: 29930100

9

Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging.

Gill JF, Delezie J, Santos G, McGuirk S, Schnyder S, Frank S, Rausch M, St-Pierre J, Handschin C. Gill JF, et al. Among authors: mcguirk s. Aging Cell. 2019 Oct;18(5):e12993. doi: 10.1111/acel.12993. Epub 2019 Jul 10. Aging Cell. 2019. PMID: 31290266 Free PMC article.

10

Metabolic Fitness and Plasticity in Cancer Progression.

McGuirk S, Audet-Delage Y, St-Pierre J. McGuirk S, et al. Trends Cancer. 2020 Jan;6(1):49-61. doi: 10.1016/j.trecan.2019.11.009. Epub 2020 Jan 3. Trends Cancer. 2020. PMID: 31952781 Review.

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