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Page 1
Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis.
Serrano-Maciá M, Simón J, González-Rellan MJ, Azkargorta M, Goikoetxea-Usandizaga N, Lopitz-Otsoa F, De Urturi DS, Rodríguez-Agudo R, Lachiondo-Ortega S, Mercado-Gomez M, Gutiérrez de Juan V, Bizkarguenaga M, Fernández-Ramos D, Buque X, Baselli GA, Valenti LVC, Iruzubieta P, Crespo J, Villa E, Banales JM, Avila MA, Marin JJG, Aspichueta P, Sutherland J, Barrio R, Mayor U, Elortza F, Xirodimas DP, Nogueiras R, Delgado TC, Martínez-Chantar ML. Serrano-Maciá M, et al. Among authors: gutierrez de juan v. Mol Metab. 2021 Nov;53:101275. doi: 10.1016/j.molmet.2021.101275. Epub 2021 Jun 18. Mol Metab. 2021. PMID: 34153521 Free PMC article.
Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation.
Embade N, Fernández-Ramos D, Varela-Rey M, Beraza N, Sini M, Gutiérrez de Juan V, Woodhoo A, Martínez-López N, Rodríguez-Iruretagoyena B, Bustamante FJ, de la Hoz AB, Carracedo A, Xirodimas DP, Rodríguez MS, Lu SC, Mato JM, Martínez-Chantar ML. Embade N, et al. Among authors: gutierrez de juan v, de la hoz ab. Hepatology. 2012 Apr;55(4):1237-48. doi: 10.1002/hep.24795. Epub 2012 Mar 1. Hepatology. 2012. PMID: 22095636 Free PMC article.
Human antigen R contributes to hepatic stellate cell activation and liver fibrosis.
Woodhoo A, Iruarrizaga-Lejarreta M, Beraza N, García-Rodríguez JL, Embade N, Fernández-Ramos D, Martínez-López N, Gutiérrez-De Juan V, Arteta B, Caballeria J, Lu SC, Mato JM, Varela-Rey M, Martínez-Chantar ML. Woodhoo A, et al. Among authors: gutierrez de juan v. Hepatology. 2012 Nov;56(5):1870-82. doi: 10.1002/hep.25828. Epub 2012 Oct 9. Hepatology. 2012. PMID: 22576182 Free PMC article.
SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
García-Rodríguez JL, Barbier-Torres L, Fernández-Álvarez S, Gutiérrez-de Juan V, Monte MJ, Halilbasic E, Herranz D, Álvarez L, Aspichueta P, Marín JJ, Trauner M, Mato JM, Serrano M, Beraza N, Martínez-Chantar ML. García-Rodríguez JL, et al. Among authors: gutierrez de juan v. Hepatology. 2014 May;59(5):1972-83. doi: 10.1002/hep.26971. Epub 2014 Mar 31. Hepatology. 2014. PMID: 24338587 Free PMC article.
S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease.
Martínez-Uña M, Varela-Rey M, Mestre D, Fernández-Ares L, Fresnedo O, Fernandez-Ramos D, Gutiérrez-de Juan V, Martin-Guerrero I, García-Orad A, Luka Z, Wagner C, Lu SC, García-Monzón C, Finnell RH, Aurrekoetxea I, Buqué X, Martínez-Chantar ML, Mato JM, Aspichueta P. Martínez-Uña M, et al. Among authors: gutierrez de juan v. J Hepatol. 2015 Mar;62(3):673-81. doi: 10.1016/j.jhep.2014.10.019. Epub 2014 Oct 18. J Hepatol. 2015. PMID: 25457203 Free PMC article.
TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency.
Fernández-Álvarez S, Gutiérrez-de Juan V, Zubiete-Franco I, Barbier-Torres L, Lahoz A, Parés A, Luka Z, Wagner C, Lu SC, Mato JM, Martínez-Chantar ML, Beraza N. Fernández-Álvarez S, et al. Among authors: gutierrez de juan v. Lab Invest. 2015 Feb;95(2):223-36. doi: 10.1038/labinvest.2014.151. Epub 2014 Dec 22. Lab Invest. 2015. PMID: 25531568 Free PMC article.
Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer.
Barbier-Torres L, Delgado TC, García-Rodríguez JL, Zubiete-Franco I, Fernández-Ramos D, Buqué X, Cano A, Gutiérrez-de Juan V, Fernández-Domínguez I, Lopitz-Otsoa F, Fernández-Tussy P, Boix L, Bruix J, Villa E, Castro A, Lu SC, Aspichueta P, Xirodimas D, Varela-Rey M, Mato JM, Beraza N, Martínez-Chantar ML. Barbier-Torres L, et al. Among authors: gutierrez de juan v. Oncotarget. 2015 Feb 10;6(4):2509-23. doi: 10.18632/oncotarget.3191. Oncotarget. 2015. PMID: 25650664 Free PMC article.
Deregulated neddylation in liver fibrosis.
Zubiete-Franco I, Fernández-Tussy P, Barbier-Torres L, Simon J, Fernández-Ramos D, Lopitz-Otsoa F, Gutiérrez-de Juan V, de Davalillo SL, Duce AM, Iruzubieta P, Taibo D, Crespo J, Caballeria J, Villa E, Aurrekoetxea I, Aspichueta P, Varela-Rey M, Lu SC, Mato JM, Beraza N, Delgado TC, Martínez-Chantar ML. Zubiete-Franco I, et al. Among authors: de davalillo sl, gutierrez de juan v. Hepatology. 2017 Feb;65(2):694-709. doi: 10.1002/hep.28933. Epub 2016 Dec 30. Hepatology. 2017. PMID: 28035772 Free PMC article.
A morphological method for ammonia detection in liver.
Gutiérrez-de-Juan V, López de Davalillo S, Fernández-Ramos D, Barbier-Torres L, Zubiete-Franco I, Fernández-Tussy P, Simon J, Lopitz-Otsoa F, de Las Heras J, Iruzubieta P, Arias-Loste MT, Villa E, Crespo J, Andrade R, Lucena MI, Varela-Rey M, Lu SC, Mato JM, Delgado TC, Martínez-Chantar ML. Gutiérrez-de-Juan V, et al. Among authors: de las heras j. PLoS One. 2017 Mar 20;12(3):e0173914. doi: 10.1371/journal.pone.0173914. eCollection 2017. PLoS One. 2017. PMID: 28319158 Free PMC article.
28 results