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The extent of protein hydration dictates the preference for heterogeneous or homogeneous nucleation generating either parallel or antiparallel β-sheet α-synuclein aggregates.
Camino JD, Gracia P, Chen SW, Sot J, de la Arada I, Sebastián V, Arrondo JLR, Goñi FM, Dobson CM, Cremades N. Camino JD, et al. Among authors: gracia p. Chem Sci. 2020 Oct 15;11(43):11902-11914. doi: 10.1039/d0sc05297c. eCollection 2020 Nov 21. Chem Sci. 2020. PMID: 33520152 Free PMC article.
Ultrafast Protein Folding in Membrane-Mimetic Environments.
Krainer G, Hartmann A, Anandamurugan A, Gracia P, Keller S, Schlierf M. Krainer G, et al. Among authors: gracia p. J Mol Biol. 2018 Feb 16;430(4):554-564. doi: 10.1016/j.jmb.2017.10.031. Epub 2017 Nov 8. J Mol Biol. 2018. PMID: 29128595
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