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Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates.
Gauvain G, Akolkar H, Chaffiol A, Arcizet F, Khoei MA, Desrosiers M, Jaillard C, Caplette R, Marre O, Bertin S, Fovet CM, Demilly J, Forster V, Brazhnikova E, Hantraye P, Pouget P, Douar A, Pruneau D, Chavas J, Sahel JA, Dalkara D, Duebel J, Benosman R, Picaud S. Gauvain G, et al. Among authors: chaffiol a. Commun Biol. 2021 Jan 27;4(1):125. doi: 10.1038/s42003-020-01594-w. Commun Biol. 2021. PMID: 33504896 Free PMC article.
In vivo optogenetic stimulation of the primate retina activates the visual cortex after long-term transduction.
Chaffiol A, Provansal M, Joffrois C, Blaize K, Labernede G, Goulet R, Burban E, Brazhnikova E, Duebel J, Pouget P, Sahel JA, Picaud S, Arcizet F, Gauvain G. Chaffiol A, et al. Mol Ther Methods Clin Dev. 2021 Nov 22;24:1-10. doi: 10.1016/j.omtm.2021.11.009. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2021. PMID: 34977267 Free PMC article.
Restoration of visual function by transplantation of optogenetically engineered photoreceptors.
Garita-Hernandez M, Lampič M, Chaffiol A, Guibbal L, Routet F, Santos-Ferreira T, Gasparini S, Borsch O, Gagliardi G, Reichman S, Picaud S, Sahel JA, Goureau O, Ader M, Dalkara D, Duebel J. Garita-Hernandez M, et al. Among authors: chaffiol a. Nat Commun. 2019 Oct 4;10(1):4524. doi: 10.1038/s41467-019-12330-2. Nat Commun. 2019. PMID: 31586094 Free PMC article.
Noninvasive gene delivery to foveal cones for vision restoration.
Khabou H, Garita-Hernandez M, Chaffiol A, Reichman S, Jaillard C, Brazhnikova E, Bertin S, Forster V, Desrosiers M, Winckler C, Goureau O, Picaud S, Duebel J, Sahel JA, Dalkara D. Khabou H, et al. Among authors: chaffiol a. JCI Insight. 2018 Jan 25;3(2):e96029. doi: 10.1172/jci.insight.96029. eCollection 2018 Jan 25. JCI Insight. 2018. PMID: 29367457 Free PMC article.
Optogenetic Light Sensors in Human Retinal Organoids.
Garita-Hernandez M, Guibbal L, Toualbi L, Routet F, Chaffiol A, Winckler C, Harinquet M, Robert C, Fouquet S, Bellow S, Sahel JA, Goureau O, Duebel J, Dalkara D. Garita-Hernandez M, et al. Among authors: chaffiol a. Front Neurosci. 2018 Nov 2;12:789. doi: 10.3389/fnins.2018.00789. eCollection 2018. Front Neurosci. 2018. PMID: 30450028 Free PMC article.
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