Zhi X - Search Results

1

RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.

Hu Y, Li X, Zhi X, Cong W, Huang B, Chen H, Wang Y, Li Y, Wang L, Fang C, Guo J, Liu Y, Cui J, Cao L, Weng W, Zhou Q, Wang S, Chen X, Su J. Hu Y, et al. Among authors: zhi x. EMBO Rep. 2021 Jul 5;22(7):e52481. doi: 10.15252/embr.202152481. Epub 2021 Jun 13. EMBO Rep. 2021. PMID: 34121311 Free PMC article.

2

Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis.

Chen X, Zhi X, Pan P, Cui J, Cao L, Weng W, Zhou Q, Wang L, Zhai X, Zhao Q, Hu H, Huang B, Su J. Chen X, et al. Among authors: zhi x. FASEB J. 2017 Nov;31(11):4855-4865. doi: 10.1096/fj.201700316R. Epub 2017 Jul 24. FASEB J. 2017. PMID: 28739641 Free PMC article.

Our study demonstrates that matrine inhibits osteoclastogenesis through modulation of multiple pathways and that matrine is a promising agent in the treatment of osteoclast-related diseases such as osteoporosis.-Chen, X., Zhi, X., Pan, P., Cui, J., Cao, L., W …

Our study demonstrates that matrine inhibits osteoclastogenesis through modulation of multiple pathways and that matrine is a promising agen …

3

l-tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK-TRAF6 interactions and inhibiting NF-κB and MAPK pathways.

Zhi X, Wang L, Chen H, Fang C, Cui J, Hu Y, Cao L, Weng W, Zhou Q, Qin L, Song H, Wang Y, Wang Y, Jiang H, Li X, Wang S, Chen X, Su J. Zhi X, et al. J Cell Mol Med. 2020 Jan;24(1):785-798. doi: 10.1111/jcmm.14790. Epub 2019 Nov 14. J Cell Mol Med. 2020. PMID: 31725199 Free PMC article.

4

Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C-Src and inhibiting NF-κB, MAPK and AKT pathways.

Zhi X, Fang C, Gu Y, Chen H, Chen X, Cui J, Hu Y, Weng W, Zhou Q, Wang Y, Wang Y, Jiang H, Li X, Cao L, Chen X, Su J. Zhi X, et al. J Cell Mol Med. 2020 May;24(9):5122-5134. doi: 10.1111/jcmm.15153. Epub 2020 Mar 17. J Cell Mol Med. 2020. PMID: 32185887 Free PMC article.

5

Triptolide prevents bone loss via suppressing osteoclastogenesis through inhibiting PI3K-AKT-NFATc1 pathway.

Cui J, Li X, Wang S, Su Y, Chen X, Cao L, Zhi X, Qiu Z, Wang Y, Jiang H, Huang B, Ji F, Su J. Cui J, et al. Among authors: zhi x. J Cell Mol Med. 2020 Jun;24(11):6149-6161. doi: 10.1111/jcmm.15229. Epub 2020 Apr 28. J Cell Mol Med. 2020. PMID: 32347017 Free PMC article.

6

Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling-mediated TRAF6 and c-Src recruitment and NF-κB, MAPK and Akt pathways.

Chen H, Fang C, Zhi X, Song S, Gu Y, Chen X, Cui J, Hu Y, Weng W, Zhou Q, Wang Y, Wang Y, Jiang H, Li X, Cao L, Chen X, Su J. Chen H, et al. Among authors: zhi x. J Cell Mol Med. 2020 Aug;24(16):9067-9084. doi: 10.1111/jcmm.15543. Epub 2020 Jun 30. J Cell Mol Med. 2020. PMID: 32604472 Free PMC article.

7

Targeting actin-bundling protein L-plastin as an anabolic therapy for bone loss.

Li X, Wang L, Huang B, Gu Y, Luo Y, Zhi X, Hu Y, Zhang H, Gu Z, Cui J, Cao L, Guo J, Wang Y, Zhou Q, Jiang H, Fang C, Weng W, Chen X, Chen X, Su J. Li X, et al. Among authors: zhi x. Sci Adv. 2020 Nov 18;6(47):eabb7135. doi: 10.1126/sciadv.abb7135. Print 2020 Nov. Sci Adv. 2020. PMID: 33208358 Free PMC article.

8

Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis.

Chen X, Zhi X, Cao L, Weng W, Pan P, Hu H, Liu C, Zhao Q, Zhou Q, Cui J, Su J. Chen X, et al. Among authors: zhi x. Cell Death Dis. 2017 Sep 7;8(9):e3037. doi: 10.1038/cddis.2017.394. Cell Death Dis. 2017. Retraction in: Cell Death Dis. 2022 Mar 11;13(3):225. doi: 10.1038/s41419-022-04697-w. PMID: 28880271 Free PMC article. Retracted.

9

Structure-based development of an osteoprotegerin-like glycopeptide that blocks RANKL/RANK interactions and reduces ovariectomy-induced bone loss in mice.

Liu C, Chen X, Zhi X, Weng W, Li Q, Li X, Zou Y, Su J, Hu HG. Liu C, et al. Among authors: zhi x. Eur J Med Chem. 2018 Feb 10;145:661-672. doi: 10.1016/j.ejmech.2018.01.022. Epub 2018 Jan 10. Eur J Med Chem. 2018. PMID: 29348072

10

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK-TRAF6 Interactions and NF-κB and MAPK Signaling Pathways.

Chen X, Zhi X, Yin Z, Li X, Qin L, Qiu Z, Su J. Chen X, et al. Among authors: zhi x. Front Pharmacol. 2018 Jun 20;9:647. doi: 10.3389/fphar.2018.00647. eCollection 2018. Front Pharmacol. 2018. PMID: 29973878 Free PMC article.

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