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PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart.
Li Q, Li C, Elnwasany A, Sharma G, An YA, Zhang G, Elhelaly WM, Lin J, Gong Y, Chen G, Wang M, Zhao S, Dai C, Smart CD, Liu J, Luo X, Deng Y, Tan L, Lv SJ, Davidson SM, Locasale JW, Lorenzi PL, Malloy CR, Gillette TG, Vander Heiden MG, Scherer PE, Szweda LI, Fu G, Wang ZV. Li Q, et al. Among authors: vander heiden mg. Circulation. 2021 Aug 31;144(9):712-727. doi: 10.1161/CIRCULATIONAHA.121.054885. Epub 2021 Jun 9. Circulation. 2021. PMID: 34102853 Free PMC article.
Cancer's insatiable appetite.
Locasale JW, Cantley LC, Vander Heiden MG. Locasale JW, et al. Among authors: vander heiden mg. Nat Biotechnol. 2009 Oct;27(10):916-7. doi: 10.1038/nbt1009-916. Nat Biotechnol. 2009. PMID: 19816448 Free PMC article.
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
Vander Heiden MG, Locasale JW, Swanson KD, Sharfi H, Heffron GJ, Amador-Noguez D, Christofk HR, Wagner G, Rabinowitz JD, Asara JM, Cantley LC. Vander Heiden MG, et al. Science. 2010 Sep 17;329(5998):1492-9. doi: 10.1126/science.1188015. Science. 2010. PMID: 20847263 Free PMC article.
Rewiring of glycolysis in cancer cell metabolism.
Locasale JW, Vander Heiden MG, Cantley LC. Locasale JW, et al. Among authors: vander heiden mg. Cell Cycle. 2010 Nov 1;9(21):4253. doi: 10.4161/cc.9.21.13925. Epub 2010 Nov 7. Cell Cycle. 2010. PMID: 21045562 No abstract available.
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Locasale JW, et al. Among authors: vander heiden mg. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. Nat Genet. 2011. PMID: 21804546 Free PMC article.
PHGDH amplification and altered glucose metabolism in human melanoma.
Mullarky E, Mattaini KR, Vander Heiden MG, Cantley LC, Locasale JW. Mullarky E, et al. Among authors: vander heiden mg. Pigment Cell Melanoma Res. 2011 Dec;24(6):1112-5. doi: 10.1111/j.1755-148X.2011.00919.x. Epub 2011 Oct 28. Pigment Cell Melanoma Res. 2011. PMID: 21981974 Review.
Metabolic pathway alterations that support cell proliferation.
Vander Heiden MG, Lunt SY, Dayton TL, Fiske BP, Israelsen WJ, Mattaini KR, Vokes NI, Stephanopoulos G, Cantley LC, Metallo CM, Locasale JW. Vander Heiden MG, et al. Cold Spring Harb Symp Quant Biol. 2011;76:325-34. doi: 10.1101/sqb.2012.76.010900. Epub 2012 Jan 19. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22262476 Review.
METabolic adaptations in the tumor MYCroenvironment.
Davidson SM, Vander Heiden MG. Davidson SM, et al. Among authors: vander heiden mg. Cell Metab. 2012 Feb 8;15(2):131-3. doi: 10.1016/j.cmet.2012.01.005. Cell Metab. 2012. PMID: 22326214 Free article.
250 results