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NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells.
Geles KG, Gao Y, Giannakou A, Sridharan L, Yamin TT, Zhang J, Karim R, Bard J, Piche-Nicholas N, Charati M, Maderna A, Lucas J, Golas J, Guffroy M, Pirie-Shepherd S, Roy M, Qian J, Franks T, Zhong W, O'Donnell CJ, Tchistiakova L, Gerber HP, Sapra P. Geles KG, et al. Among authors: gao y. Cell Rep Med. 2021 May 18;2(5):100279. doi: 10.1016/j.xcrm.2021.100279. eCollection 2021 May 18. Cell Rep Med. 2021. PMID: 34095881 Free PMC article.
Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells.
Qiu M, Peng Q, Jiang I, Carroll C, Han G, Rymer I, Lippincott J, Zachwieja J, Gajiwala K, Kraynov E, Thibault S, Stone D, Gao Y, Sofia S, Gallo J, Li G, Yang J, Li K, Wei P. Qiu M, et al. Among authors: gao y. Cancer Lett. 2013 Jan 28;328(2):261-70. doi: 10.1016/j.canlet.2012.09.023. Epub 2012 Oct 3. Cancer Lett. 2013. PMID: 23041621
Metabolic Engineering of Glycofusion Bispecific Antibodies for α-Dystroglycanopathies.
Zhong X, Yan GG, Chaturvedi A, Li X, Gao Y, Girgenrath M, Corcoran CJ, Diblasio-Smith L, LaVallie ER, de Rham T, Zhou J, Abel M, Riegel L, Lim SKH, Bloom L, Lin L, D'Antona AM. Zhong X, et al. Among authors: gao y. Antibodies (Basel). 2024 Oct 7;13(4):83. doi: 10.3390/antib13040083. Antibodies (Basel). 2024. PMID: 39449325 Free PMC article.
Structure of bone morphogenetic protein 9 procomplex.
Mi LZ, Brown CT, Gao Y, Tian Y, Le VQ, Walz T, Springer TA. Mi LZ, et al. Among authors: gao y. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3710-5. doi: 10.1073/pnas.1501303112. Epub 2015 Mar 6. Proc Natl Acad Sci U S A. 2015. PMID: 25751889 Free PMC article.
Regulation of GDF-8 signaling by the p38 MAPK.
Philip B, Lu Z, Gao Y. Philip B, et al. Among authors: gao y. Cell Signal. 2005 Mar;17(3):365-75. doi: 10.1016/j.cellsig.2004.08.003. Cell Signal. 2005. PMID: 15567067
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