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Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers.
Mondal S, Roy D, Sarkar Bhattacharya S, Jin L, Jung D, Zhang S, Kalogera E, Staub J, Wang Y, Xuyang W, Khurana A, Chien J, Telang S, Chesney J, Tapolsky G, Petras D, Shridhar V. Mondal S, et al. Among authors: jin l. Int J Cancer. 2019 Jan 1;144(1):178-189. doi: 10.1002/ijc.31868. Epub 2018 Oct 30. Int J Cancer. 2019. PMID: 30226266 Free PMC article.
Genes associated with bowel metastases in ovarian cancer.
Mariani A, Wang C, Oberg AL, Riska SM, Torres M, Kumka J, Multinu F, Sagar G, Roy D, Jung DB, Zhang Q, Grassi T, Visscher DW, Patel VP, Jin L, Staub JK, Cliby WA, Weroha SJ, Kalli KR, Hartmann LC, Kaufmann SH, Goode EL, Shridhar V. Mariani A, et al. Among authors: jin l. Gynecol Oncol. 2019 Sep;154(3):495-504. doi: 10.1016/j.ygyno.2019.06.010. Epub 2019 Jun 14. Gynecol Oncol. 2019. PMID: 31204077 Free PMC article.
Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer.
Ray U, Jung DB, Jin L, Xiao Y, Dasari S, Sarkar Bhattacharya S, Thirusangu P, Staub JK, Roy D, Roy B, Weroha SJ, Hou X, Purcell JW, Bakkum-Gamez JN, Kaufmann SH, Kannan N, Mitra AK, Shridhar V. Ray U, et al. Among authors: jin l. Cancer Res. 2022 Mar 15;82(6):1038-1054. doi: 10.1158/0008-5472.CAN-21-0622. Cancer Res. 2022. PMID: 34654724 Free PMC article.
PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM.
Sarkar Bhattacharya S, Thirusangu P, Jin L, Staub J, Shridhar V, Molina JR. Sarkar Bhattacharya S, et al. Among authors: jin l. Br J Cancer. 2022 Oct;127(7):1352-1364. doi: 10.1038/s41416-022-01867-7. Epub 2022 Jul 6. Br J Cancer. 2022. PMID: 35794237 Free PMC article.
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