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Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.
El Manaa W, Duplan E, Goiran T, Lauritzen I, Vaillant Beuchot L, Lacas-Gervais S, Morais VA, You H, Qi L, Salazar M, Ozcan U, Chami M, Checler F, Alves da Costa C. El Manaa W, et al. Among authors: morais va. Autophagy. 2021 Dec;17(12):4363-4385. doi: 10.1080/15548627.2021.1917129. Epub 2021 May 24. Autophagy. 2021. PMID: 34030589 Free PMC article.
β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.
Goiran T, Duplan E, Chami M, Bourgeois A, El Manaa W, Rouland L, Dunys J, Lauritzen I, You H, Stambolic V, Biféri MG, Barkats M, Pimplikar SW, Sergeant N, Colin M, Morais VA, Pardossi-Piquard R, Checler F, Alves da Costa C. Goiran T, et al. Among authors: morais va. Biol Psychiatry. 2018 Mar 1;83(5):416-427. doi: 10.1016/j.biopsych.2017.04.011. Epub 2017 May 3. Biol Psychiatry. 2018. PMID: 28587718 Free article.
PINK1 activation-turning on a promiscuous kinase.
Aerts L, De Strooper B, Morais VA. Aerts L, et al. Among authors: morais va. Biochem Soc Trans. 2015 Apr;43(2):280-6. doi: 10.1042/BST20150002. Biochem Soc Trans. 2015. PMID: 25849930 Review.
59 results