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Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition.
Mao W, Ghasemzadeh A, Freeman ZT, Obradovic A, Chaimowitz MG, Nirschl TR, McKiernan E, Yegnasubramanian S, Drake CG. Mao W, et al. Among authors: obradovic a. J Immunother Cancer. 2019 Oct 25;7(1):277. doi: 10.1186/s40425-019-0758-y. J Immunother Cancer. 2019. PMID: 31653272 Free PMC article.
T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer.
Obradovic AZ, Dallos MC, Zahurak ML, Partin AW, Schaeffer EM, Ross AE, Allaf ME, Nirschl TR, Liu D, Chapman CG, O'Neal T, Cao H, Durham JN, Guner G, Baena-Del Valle JA, Ertunc O, De Marzo AM, Antonarakis ES, Drake CG. Obradovic AZ, et al. Clin Cancer Res. 2020 Jul 1;26(13):3182-3192. doi: 10.1158/1078-0432.CCR-19-3372. Epub 2020 Mar 15. Clin Cancer Res. 2020. PMID: 32173650 Free PMC article.
Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses.
Aggen DH, Ager CR, Obradovic AZ, Chowdhury N, Ghasemzadeh A, Mao W, Chaimowitz MG, Lopez-Bujanda ZA, Spina CS, Hawley JE, Dallos MC, Zhang C, Wang V, Li H, Guo XV, Drake CG. Aggen DH, et al. Among authors: obradovic az. Clin Cancer Res. 2021 Jan 15;27(2):608-621. doi: 10.1158/1078-0432.CCR-20-1610. Epub 2020 Nov 4. Clin Cancer Res. 2021. PMID: 33148676 Free PMC article.
TGM4: an immunogenic prostate-restricted antigen.
Lopez-Bujanda ZA, Obradovic A, Nirschl TR, Crowley L, Macedo R, Papachristodoulou A, O'Donnell T, Laserson U, Zarif JC, Reshef R, Yuan T, Soni MK, Antonarakis ES, Haffner MC, Larman HB, Shen MM, Muranski P, Drake CG. Lopez-Bujanda ZA, et al. Among authors: obradovic a. J Immunother Cancer. 2021 Jun;9(6):e001649. doi: 10.1136/jitc-2020-001649. J Immunother Cancer. 2021. PMID: 34193566 Free PMC article.
BCG invokes superior STING-mediated innate immune response over radiotherapy in a carcinogen murine model of urothelial cancer.
Lombardo KA, Obradovic A, Singh AK, Liu JL, Joice G, Kates M, Bishai W, McConkey D, Chaux A, Eich ML, Rezaei MK, Netto GJ, Drake CG, Tran P, Matoso A, Bivalacqua TJ. Lombardo KA, et al. Among authors: obradovic a. J Pathol. 2022 Feb;256(2):223-234. doi: 10.1002/path.5830. Epub 2021 Dec 10. J Pathol. 2022. PMID: 34731491 Free PMC article.
Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression.
Lopez-Bujanda ZA, Haffner MC, Chaimowitz MG, Chowdhury N, Venturini NJ, Patel RA, Obradovic A, Hansen CS, Jacków J, Maynard JP, Sfanos KS, Abate-Shen C, Bieberich CJ, Hurley PJ, Selby MJ, Korman AJ, Christiano AM, De Marzo AM, Drake CG. Lopez-Bujanda ZA, et al. Among authors: obradovic a. Nat Cancer. 2021 Aug;2(8):803-818. doi: 10.1038/s43018-021-00227-3. Epub 2021 Jul 19. Nat Cancer. 2021. PMID: 35122025 Free PMC article.
Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators.
Obradovic A, Ager C, Turunen M, Nirschl T, Khosravi-Maharlooei M, Iuga A, Jackson CM, Yegnasubramanian S, Tomassoni L, Fernandez EC, McCann P, Rogava M, DeMarzo AM, Kochel CM, Allaf M, Bivalacqua T, Lim M, Realubit R, Karan C, Drake CG, Califano A. Obradovic A, et al. Cancer Cell. 2023 May 8;41(5):933-949.e11. doi: 10.1016/j.ccell.2023.04.003. Epub 2023 Apr 27. Cancer Cell. 2023. PMID: 37116491 Free PMC article.
122 results