Cystathionine γ-lyase deficiency aggravates obesity-related insulin resistance via FoxO1-dependent hepatic gluconeogenesis.
Guo W, Li D, You Y, Li W, Hu B, Zhang S, Miao L, Xian M, Zhu Y, Shen X.
Guo W, et al. Among authors: zhang s.
FASEB J. 2019 Mar;33(3):4212-4224. doi: 10.1096/fj.201801894R. Epub 2018 Dec 10.
FASEB J. 2019.
PMID: 30526049
Our study reveals a double-edged sword effect and a novel mechanism for CSE/H(2)S in obesity associated with insulin resistance and provides evidence for CSE/H(2)S as a promising therapeutic potential target for obesity-related insulin resistance.-Guo, W., Li, D., Y …
Our study reveals a double-edged sword effect and a novel mechanism for CSE/H(2)S in obesity associated with insulin resistance and p …