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Page 1
Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury.
Iruzubieta P, Goikoetxea-Usandizaga N, Barbier-Torres L, Serrano-Maciá M, Fernández-Ramos D, Fernández-Tussy P, Gutiérrez-de-Juan V, Lachiondo-Ortega S, Simon J, Bravo M, Lopitz-Otsoa F, Robles M, Ferre-Aracil C, Varela-Rey M, Elguezabal N, Calleja JL, Lu SC, Milkiewicz M, Milkiewicz P, Anguita J, Monte MJ, Marin JJG, López-Hoyos M, Delgado TC, Rincón M, Crespo J, Martínez-Chantar ML. Iruzubieta P, et al. Among authors: rincon m. JHEP Rep. 2021 Mar 18;3(3):100276. doi: 10.1016/j.jhepr.2021.100276. eCollection 2021 Jun. JHEP Rep. 2021. PMID: 33997750 Free PMC article.
Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1.
Diehl S, Anguita J, Hoffmeyer A, Zapton T, Ihle JN, Fikrig E, Rincón M. Diehl S, et al. Among authors: rincon m. Immunity. 2000 Dec;13(6):805-15. doi: 10.1016/s1074-7613(00)00078-9. Immunity. 2000. PMID: 11163196 Free article.
MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations.
Hatle KM, Gummadidala P, Navasa N, Bernardo E, Dodge J, Silverstrim B, Fortner K, Burg E, Suratt BT, Hammer J, Radermacher M, Taatjes DJ, Thornton T, Anguita J, Rincon M. Hatle KM, et al. Among authors: rincon m. Mol Cell Biol. 2013 Jun;33(11):2302-14. doi: 10.1128/MCB.00189-13. Epub 2013 Mar 25. Mol Cell Biol. 2013. PMID: 23530063 Free PMC article.
Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults.
Navasa N, Martín I, Iglesias-Pedraz JM, Beraza N, Atondo E, Izadi H, Ayaz F, Fernández-Álvarez S, Hatle K, Som A, Dienz O, Osborne BA, Martínez-Chantar ML, Rincón M, Anguita J. Navasa N, et al. Among authors: rincon m. J Infect Dis. 2015 Jan 1;211(1):135-45. doi: 10.1093/infdis/jiu389. Epub 2014 Jul 14. J Infect Dis. 2015. PMID: 25028693 Free PMC article.
Ikaros mediates the DNA methylation-independent silencing of MCJ/DNAJC15 gene expression in macrophages.
Navasa N, Martin-Ruiz I, Atondo E, Sutherland JD, Angel Pascual-Itoiz M, Carreras-González A, Izadi H, Tomás-Cortázar J, Ayaz F, Martin-Martin N, Torres IM, Barrio R, Carracedo A, Olivera ER, Rincón M, Anguita J. Navasa N, et al. Among authors: rincon m. Sci Rep. 2015 Sep 30;5:14692. doi: 10.1038/srep14692. Sci Rep. 2015. PMID: 26419808 Free PMC article.
Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus.
Champagne DP, Hatle KM, Fortner KA, D'Alessandro A, Thornton TM, Yang R, Torralba D, Tomás-Cortázar J, Jun YW, Ahn KH, Hansen KC, Haynes L, Anguita J, Rincon M. Champagne DP, et al. Among authors: rincon m. Immunity. 2016 Jun 21;44(6):1299-311. doi: 10.1016/j.immuni.2016.02.018. Epub 2016 May 24. Immunity. 2016. PMID: 27234056 Free PMC article.
The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.
Barbier-Torres L, Iruzubieta P, Fernández-Ramos D, Delgado TC, Taibo D, Guitiérrez-de-Juan V, Varela-Rey M, Azkargorta M, Navasa N, Fernández-Tussy P, Zubiete-Franco I, Simon J, Lopitz-Otsoa F, Lachiondo-Ortega S, Crespo J, Masson S, McCain MV, Villa E, Reeves H, Elortza F, Lucena MI, Hernández-Alvarez MI, Zorzano A, Andrade RJ, Lu SC, Mato JM, Anguita J, Rincón M, Martínez-Chantar ML. Barbier-Torres L, et al. Among authors: rincon m. Nat Commun. 2017 Dec 12;8(1):2068. doi: 10.1038/s41467-017-01970-x. Nat Commun. 2017. PMID: 29233977 Free PMC article.
miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease.
Fernández-Tussy P, Fernández-Ramos D, Lopitz-Otsoa F, Simón J, Barbier-Torres L, Gomez-Santos B, Nuñez-Garcia M, Azkargorta M, Gutiérrez-de Juan V, Serrano-Macia M, Rodríguez-Agudo R, Iruzubieta P, Anguita J, Castro RE, Champagne D, Rincón M, Elortza F, Arslanow A, Krawczyk M, Lammert F, Kirchmeyer M, Behrmann I, Crespo J, Lu SC, Mato JM, Varela-Rey M, Aspichueta P, Delgado TC, Martínez-Chantar ML. Fernández-Tussy P, et al. Among authors: rincon m. Mol Metab. 2019 Nov;29:40-54. doi: 10.1016/j.molmet.2019.08.008. Epub 2019 Aug 16. Mol Metab. 2019. PMID: 31668391 Free PMC article.
416 results