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Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer.
Zhou Q, Chen W, Fan Z, Chen Z, Liang J, Zeng G, Liu L, Liu W, Yang T, Cao X, Yu B, Xu M, Chen YG, Chen L. Zhou Q, et al. Among authors: liu l, liu w. Theranostics. 2021 May 3;11(13):6592-6606. doi: 10.7150/thno.59816. eCollection 2021. Theranostics. 2021. PMID: 33995678 Free PMC article.
In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
Wu Q, Tian Y, Zhang J, Tong X, Huang H, Li S, Zhao H, Tang Y, Yuan C, Wang K, Fang Z, Gao L, Hu X, Li F, Qin Z, Yao S, Chen T, Chen H, Zhang G, Liu W, Sun Y, Chen L, Wong KK, Ge K, Chen L, Ji H. Wu Q, et al. Among authors: liu w. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3978-E3986. doi: 10.1073/pnas.1716589115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632194 Free PMC article.
Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition.
Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, Zhou Q, Zeng G, Hu X, Yu L, Zhou S, Tong X, Huang H, Chen H, Liu Q, Liu W, Zhang G, Zeng M, Zhou G, He Q, Ji H, Chen L. Gao L, et al. Among authors: liu q, liu w. Nat Commun. 2019 Apr 10;10(1):1665. doi: 10.1038/s41467-019-09295-7. Nat Commun. 2019. PMID: 30971692 Free PMC article.
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