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Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions.
Filbin MR, Mehta A, Schneider AM, Kays KR, Guess JR, Gentili M, Fenyves BG, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Gerszten RE, Heimberg GS, Hoover PJ, Lieb DJ, Lin B, Ngo D, Pelka K, Reyes M, Smillie CS, Waghray A, Wood TE, Zajac AS, Jennings LL, Grundberg I, Bhattacharyya RP, Parry BA, Villani AC, Sade-Feldman M, Hacohen N, Goldberg MB. Filbin MR, et al. Among authors: mehta a. Cell Rep Med. 2021 May 18;2(5):100287. doi: 10.1016/j.xcrm.2021.100287. Epub 2021 May 3. Cell Rep Med. 2021. PMID: 33969320 Free PMC article.
Temporal and Spatial Heterogeneity of Host Response to SARS-CoV-2 Pulmonary Infection.
Desai N, Neyaz A, Szabolcs A, Shih AR, Chen JH, Thapar V, Nieman LT, Solovyov A, Mehta A, Lieb DJ, Kulkarni AS, Jaicks C, Pinto CJ, Juric D, Chebib I, Colvin RB, Kim AY, Monroe R, Warren SE, Danaher P, Reeves JW, Gong J, Rueckert EH, Greenbaum BD, Hacohen N, Lagana SM, Rivera MN, Sholl LM, Stone JR, Ting DT, Deshpande V. Desai N, et al. Among authors: mehta a. medRxiv [Preprint]. 2020 Aug 2:2020.07.30.20165241. doi: 10.1101/2020.07.30.20165241. medRxiv. 2020. Update in: Nat Commun. 2020 Dec 9;11(1):6319. doi: 10.1038/s41467-020-20139-7. PMID: 32766600 Free PMC article. Updated. Preprint.
Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19.
Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N. Reyes M, et al. Among authors: mehta a. bioRxiv [Preprint]. 2020 Sep 2:2020.09.02.280180. doi: 10.1101/2020.09.02.280180. bioRxiv. 2020. Update in: Sci Transl Med. 2021 Jun 16;13(598):eabe9599. doi: 10.1126/scitranslmed.abe9599. PMID: 32908980 Free PMC article. Updated. Preprint.
Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients.
Filbin MR, Mehta A, Schneider AM, Kays KR, Guess JR, Gentili M, Fenyves BG, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilly BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Gerszten RE, Heimberg GS, Hoover PJ, Lieb DJ, Lin B, Ngo D, Pelka K, Reyes M, Smillie CS, Waghray A, Wood TE, Zajac AS, Jennings LL, Grundberg I, Bhattacharyya RP, Parry BA, Villani AC, Sade-Feldman M, Hacohen N, Goldberg MB. Filbin MR, et al. Among authors: mehta a. bioRxiv [Preprint]. 2020 Nov 4:2020.11.02.365536. doi: 10.1101/2020.11.02.365536. bioRxiv. 2020. Update in: Cell Rep Med. 2021 May 18;2(5):100287. doi: 10.1016/j.xcrm.2021.100287. PMID: 33173871 Free PMC article. Updated. Preprint.
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection.
Desai N, Neyaz A, Szabolcs A, Shih AR, Chen JH, Thapar V, Nieman LT, Solovyov A, Mehta A, Lieb DJ, Kulkarni AS, Jaicks C, Xu KH, Raabe MJ, Pinto CJ, Juric D, Chebib I, Colvin RB, Kim AY, Monroe R, Warren SE, Danaher P, Reeves JW, Gong J, Rueckert EH, Greenbaum BD, Hacohen N, Lagana SM, Rivera MN, Sholl LM, Stone JR, Ting DT, Deshpande V. Desai N, et al. Among authors: mehta a. Nat Commun. 2020 Dec 9;11(1):6319. doi: 10.1038/s41467-020-20139-7. Nat Commun. 2020. PMID: 33298930 Free PMC article.
SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes.
Li Y, Schneider AM, Mehta A, Sade-Feldman M, Kays KR, Gentili M, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilly BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Parry BA, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Regan J, Flynn JP, Villani AC, Hacohen N, Goldberg MB, Filbin MR, Li JZ. Li Y, et al. Among authors: mehta a. medRxiv [Preprint]. 2021 Feb 26:2021.02.24.21252357. doi: 10.1101/2021.02.24.21252357. medRxiv. 2021. Update in: J Clin Invest. 2021 Jul 1;131(13):148635. doi: 10.1172/JCI148635. PMID: 33655257 Free PMC article. Updated. Preprint.
Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients.
Kragstrup TW, Singh HS, Grundberg I, Nielsen AL, Rivellese F, Mehta A, Goldberg MB, Filbin MR, Qvist P, Bibby BM. Kragstrup TW, et al. Among authors: mehta a. PLoS One. 2021 Jun 4;16(6):e0252799. doi: 10.1371/journal.pone.0252799. eCollection 2021. PLoS One. 2021. PMID: 34086837 Free PMC article.
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro.
Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N. Reyes M, et al. Among authors: mehta a. Sci Transl Med. 2021 Jun 16;13(598):eabe9599. doi: 10.1126/scitranslmed.abe9599. Epub 2021 Jun 8. Sci Transl Med. 2021. PMID: 34103408 Free PMC article.
SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes.
Li Y, Schneider AM, Mehta A, Sade-Feldman M, Kays KR, Gentili M, Charland NC, Gonye AL, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Parry BA, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Regan J, Flynn JP, Villani AC, Hacohen N, Goldberg MB, Filbin MR, Li JZ. Li Y, et al. Among authors: mehta a. J Clin Invest. 2021 Jul 1;131(13):e148635. doi: 10.1172/JCI148635. J Clin Invest. 2021. PMID: 34196300 Free PMC article.
5,870 results