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Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain.
Schuurs ZP, Hammond E, Elli S, Rudd TR, Mycroft-West CJ, Lima MA, Skidmore MA, Karlsson R, Chen YH, Bagdonaite I, Yang Z, Ahmed YA, Richard DJ, Turnbull J, Ferro V, Coombe DR, Gandhi NS. Schuurs ZP, et al. Among authors: rudd tr. Comput Struct Biotechnol J. 2021;19:2806-2818. doi: 10.1016/j.csbj.2021.05.002. Epub 2021 May 4. Comput Struct Biotechnol J. 2021. PMID: 33968333 Free PMC article.
Evidence for Multiple Binding Modes in the Initial Contact Between SARS-CoV-2 Spike S1 Protein and Cell Surface Glycans.
Parafioriti M, Ni M, Petitou M, Mycroft-West CJ, Rudd TR, Gandhi NS, Ferro V, Turnbull JE, Lima MA, Skidmore MA, Fernig DG, Yates EA, Bisio A, Guerrini M, Elli S. Parafioriti M, et al. Among authors: rudd tr. Chemistry. 2023 Jan 2;29(1):e202202599. doi: 10.1002/chem.202202599. Epub 2022 Nov 7. Chemistry. 2023. PMID: 36134621 Free PMC article.
Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin.
Mycroft-West CJ, Su D, Pagani I, Rudd TR, Elli S, Gandhi NS, Guimond SE, Miller GJ, Meneghetti MCZ, Nader HB, Li Y, Nunes QM, Procter P, Mancini N, Clementi M, Bisio A, Forsyth NR, Ferro V, Turnbull JE, Guerrini M, Fernig DG, Vicenzi E, Yates EA, Lima MA, Skidmore MA. Mycroft-West CJ, et al. Among authors: rudd tr. Thromb Haemost. 2020 Dec;120(12):1700-1715. doi: 10.1055/s-0040-1721319. Epub 2020 Dec 23. Thromb Haemost. 2020. PMID: 33368089 Free PMC article.
67 results