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Single-cell Transcriptomics Uncover a Novel Role of Myeloid Cells and T-lymphocytes in the Fibrotic Microenvironment in Peyronie's Disease.
Milenkovic U, Boeckx B, Lambrechts D, Janky R, Hatzichristodoulou G, van Renterghem K, Gevaert T, Cellek S, Bivalacqua TJ, De Ridder D, Albersen M. Milenkovic U, et al. Among authors: lambrechts d. Eur Urol Focus. 2022 May;8(3):814-828. doi: 10.1016/j.euf.2021.04.012. Epub 2021 May 4. Eur Urol Focus. 2022. PMID: 33962884
Genomic and epigenomic analysis of high-risk prostate cancer reveals changes in hydroxymethylation and TET1.
Spans L, Van den Broeck T, Smeets E, Prekovic S, Thienpont B, Lambrechts D, Karnes RJ, Erho N, Alshalalfa M, Davicioni E, Helsen C, Gevaert T, Tosco L, Haustermans K, Lerut E, Joniau S, Claessens F. Spans L, et al. Among authors: lambrechts d. Oncotarget. 2016 Apr 26;7(17):24326-38. doi: 10.18632/oncotarget.8220. Oncotarget. 2016. PMID: 27014907 Free PMC article.
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.
Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, Boeckx B, Wijnhoven PW, Radaelli E, Vermi W, Leucci E, Lapouge G, Beck B, van den Oord J, Nakagawa S, Hirose T, Sablina AA, Lambrechts D, Aerts S, Blanpain C, Marine JC. Adriaens C, et al. Among authors: lambrechts d. Nat Med. 2016 Aug;22(8):861-8. doi: 10.1038/nm.4135. Epub 2016 Jul 4. Nat Med. 2016. PMID: 27376578
Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
Thienpont B, Steinbacher J, Zhao H, D'Anna F, Kuchnio A, Ploumakis A, Ghesquière B, Van Dyck L, Boeckx B, Schoonjans L, Hermans E, Amant F, Kristensen VN, Peng Koh K, Mazzone M, Coleman M, Carell T, Carmeliet P, Lambrechts D. Thienpont B, et al. Among authors: d anna f, lambrechts d. Nature. 2016 Sep 1;537(7618):63-68. doi: 10.1038/nature19081. Epub 2016 Aug 17. Nature. 2016. PMID: 27533040 Free PMC article.
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.
Cantelmo AR, Conradi LC, Brajic A, Goveia J, Kalucka J, Pircher A, Chaturvedi P, Hol J, Thienpont B, Teuwen LA, Schoors S, Boeckx B, Vriens J, Kuchnio A, Veys K, Cruys B, Finotto L, Treps L, Stav-Noraas TE, Bifari F, Stapor P, Decimo I, Kampen K, De Bock K, Haraldsen G, Schoonjans L, Rabelink T, Eelen G, Ghesquière B, Rehman J, Lambrechts D, Malik AB, Dewerchin M, Carmeliet P. Cantelmo AR, et al. Among authors: lambrechts d. Cancer Cell. 2016 Dec 12;30(6):968-985. doi: 10.1016/j.ccell.2016.10.006. Epub 2016 Nov 17. Cancer Cell. 2016. PMID: 27866851 Free PMC article.
Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching.
De Smedt L, Palmans S, Andel D, Govaere O, Boeckx B, Smeets D, Galle E, Wouters J, Barras D, Suffiotti M, Dekervel J, Tousseyn T, De Hertogh G, Prenen H, Tejpar S, Lambrechts D, Sagaert X. De Smedt L, et al. Among authors: lambrechts d. Br J Cancer. 2017 Jan 3;116(1):58-65. doi: 10.1038/bjc.2016.382. Epub 2016 Nov 24. Br J Cancer. 2017. PMID: 27884016 Free PMC article.
620 results