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Page 1
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.
Si L, Bai H, Rodas M, Cao W, Oh CY, Jiang A, Moller R, Hoagland D, Oishi K, Horiuchi S, Uhl S, Blanco-Melo D, Albrecht RA, Liu WC, Jordan T, Nilsson-Payant BE, Golynker I, Frere J, Logue J, Haupt R, McGrath M, Weston S, Zhang T, Plebani R, Soong M, Nurani A, Kim SM, Zhu DY, Benam KH, Goyal G, Gilpin SE, Prantil-Baun R, Gygi SP, Powers RK, Carlson KE, Frieman M, tenOever BR, Ingber DE. Si L, et al. Among authors: hoagland d. Nat Biomed Eng. 2021 Aug;5(8):815-829. doi: 10.1038/s41551-021-00718-9. Epub 2021 May 3. Nat Biomed Eng. 2021. PMID: 33941899 Free PMC article.
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery.
Frere JJ, Serafini RA, Pryce KD, Zazhytska M, Oishi K, Golynker I, Panis M, Zimering J, Horiuchi S, Hoagland DA, Møller R, Ruiz A, Kodra A, Overdevest JB, Canoll PD, Borczuk AC, Chandar V, Bram Y, Schwartz R, Lomvardas S, Zachariou V, tenOever BR. Frere JJ, et al. Among authors: hoagland da. Sci Transl Med. 2022 Sep 28;14(664):eabq3059. doi: 10.1126/scitranslmed.abq3059. Epub 2022 Sep 28. Sci Transl Med. 2022. PMID: 35857629 Free PMC article.
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Blanco-Melo D, Nilsson-Payant BE, Liu WC, Uhl S, Hoagland D, Møller R, Jordan TX, Oishi K, Panis M, Sachs D, Wang TT, Schwartz RE, Lim JK, Albrecht RA, tenOever BR. Blanco-Melo D, et al. Among authors: hoagland d. Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15. Cell. 2020. PMID: 32416070 Free PMC article.
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.
Yang L, Nilsson-Payant BE, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Carrau L, Horiuchi S, Goff M, Lim JK, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho DD, Schwartz RE, tenOever BR, Evans T, Chen S. Yang L, et al. Among authors: hoagland d. Stem Cell Reports. 2021 Sep 14;16(9):2274-2288. doi: 10.1016/j.stemcr.2021.07.012. Epub 2021 Jul 20. Stem Cell Reports. 2021. PMID: 34403650 Free PMC article.
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, Zhang T, Kim TW, Harschnitz O, Redmond D, Houghton S, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen DT, Cioffi M, Chandar V, Hoagland DA, Huang Y, Xiang J, Wang H, Lyden D, Borczuk A, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S. Yang L, et al. Among authors: hoagland da. Cell Stem Cell. 2020 Jul 2;27(1):125-136.e7. doi: 10.1016/j.stem.2020.06.015. Epub 2020 Jun 19. Cell Stem Cell. 2020. PMID: 32579880 Free PMC article.
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells.
Daniloski Z, Jordan TX, Wessels HH, Hoagland DA, Kasela S, Legut M, Maniatis S, Mimitou EP, Lu L, Geller E, Danziger O, Rosenberg BR, Phatnani H, Smibert P, Lappalainen T, tenOever BR, Sanjana NE. Daniloski Z, et al. Cell. 2021 Jan 7;184(1):92-105.e16. doi: 10.1016/j.cell.2020.10.030. Epub 2020 Oct 24. Cell. 2021. PMID: 33147445 Free PMC article.
Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia.
Zazhytska M, Kodra A, Hoagland DA, Frere J, Fullard JF, Shayya H, McArthur NG, Moeller R, Uhl S, Omer AD, Gottesman ME, Firestein S, Gong Q, Canoll PD, Goldman JE, Roussos P, tenOever BR, Jonathan B Overdevest, Lomvardas S. Zazhytska M, et al. Among authors: hoagland da. Cell. 2022 Mar 17;185(6):1052-1064.e12. doi: 10.1016/j.cell.2022.01.024. Epub 2022 Feb 2. Cell. 2022. PMID: 35180380 Free PMC article.
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Murphy A, Iskhakova M, Fernando MB, Powell SK, Deans PJM, Javidfar B, Peter C, Møller R, Uhl SA, Garcia MF, Kimura M, Iwasawa K, Crary JF, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Dobrindt K, et al. Stem Cell Reports. 2021 Mar 9;16(3):505-518. doi: 10.1016/j.stemcr.2021.02.010. Epub 2021 Feb 13. Stem Cell Reports. 2021. PMID: 33636110 Free PMC article.
Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19.
Britton GJ, Chen-Liaw A, Cossarini F, Livanos AE, Spindler MP, Plitt T, Eggers J, Mogno I, Gonzalez-Reiche AS, Siu S, Tankelevich M, Grinspan LT, Dixon RE, Jha D, van de Guchte A, Khan Z, Martinez-Delgado G, Amanat F, Hoagland DA, tenOever BR, Dubinsky MC, Merad M, van Bakel H, Krammer F, Bongers G, Mehandru S, Faith JJ. Britton GJ, et al. Among authors: hoagland da. Sci Rep. 2021 Jun 25;11(1):13308. doi: 10.1038/s41598-021-92740-9. Sci Rep. 2021. PMID: 34172783 Free PMC article.
68 results