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Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition.
Lai LP, Brel V, Sharma K, Frappier J, Le-Henanf N, Vivet B, Muzet N, Schell E, Morales R, Rooney E, Basse N, Yi M, Lacroix F, Holderfield M, Englaro W, Marcireau C, Debussche L, Nissley DV, McCormick F. Lai LP, et al. Among authors: englaro w. SLAS Discov. 2021 Aug;26(7):922-932. doi: 10.1177/24725552211008853. Epub 2021 Apr 24. SLAS Discov. 2021. PMID: 33896272 Free PMC article.
Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.
Deng G, Shen J, Yin M, McManus J, Mathieu M, Gee P, He T, Shi C, Bedel O, McLean LR, Le-Strat F, Zhang Y, Marquette JP, Gao Q, Zhang B, Rak A, Hoffmann D, Rooney E, Vassort A, Englaro W, Li Y, Patel V, Adrian F, Gross S, Wiederschain D, Cheng H, Licht S. Deng G, et al. Among authors: englaro w. J Biol Chem. 2015 Jan 9;290(2):762-74. doi: 10.1074/jbc.M114.608497. Epub 2014 Nov 12. J Biol Chem. 2015. PMID: 25391653 Free PMC article.
Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies.
Desreumaux P, Dubuquoy L, Nutten S, Peuchmaur M, Englaro W, Schoonjans K, Derijard B, Desvergne B, Wahli W, Chambon P, Leibowitz MD, Colombel JF, Auwerx J. Desreumaux P, et al. Among authors: englaro w. J Exp Med. 2001 Apr 2;193(7):827-38. doi: 10.1084/jem.193.7.827. J Exp Med. 2001. PMID: 11283155 Free PMC article.