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Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.
Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA. Telwatte S, et al. Among authors: lee s. PLoS Pathog. 2018 Nov 15;14(11):e1007357. doi: 10.1371/journal.ppat.1007357. eCollection 2018 Nov. PLoS Pathog. 2018. PMID: 30440043 Free PMC article.
Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay.
Lee SA, Telwatte S, Hatano H, Kashuba ADM, Cottrell ML, Hoh R, Liegler TJ, Stephenson S, Somsouk M, Hunt PW, Deeks SG, Yukl S, Savic RM. Lee SA, et al. J Acquir Immune Defic Syndr. 2020 Apr 15;83(5):530-537. doi: 10.1097/QAI.0000000000002287. J Acquir Immune Defic Syndr. 2020. PMID: 32168200 Free PMC article.
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. Hsiao F, et al. Among authors: lee gq, lee s. PLoS Pathog. 2020 Apr 30;16(4):e1008450. doi: 10.1371/journal.ppat.1008450. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32353080 Free PMC article.
Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence.
Ma T, Ryu H, McGregor M, Babcock B, Neidleman J, Xie G, George AF, Frouard J, Murray V, Gill G, Ghosn E, Newell E, Lee S, Roan NR. Ma T, et al. Among authors: lee s. bioRxiv [Preprint]. 2021 Apr 29:2021.04.28.441880. doi: 10.1101/2021.04.28.441880. bioRxiv. 2021. Update in: J Immunol. 2021 Sep 1;207(5):1344-1356. doi: 10.4049/jimmunol.2100465. PMID: 33948597 Free PMC article. Updated. Preprint.
mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status.
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. Neidleman J, et al. bioRxiv [Preprint]. 2021 Jul 29:2021.05.12.443888. doi: 10.1101/2021.05.12.443888. bioRxiv. 2021. Update in: Elife. 2021 Oct 12;10:e72619. doi: 10.7554/eLife.72619. PMID: 34013277 Free PMC article. Updated. Preprint.
A common allele of HLA mediates asymptomatic SARS-CoV-2 infection.
Augusto DG, Yusufali T, Sabatino JJ Jr, Peyser ND, Murdolo LD, Butcher X, Murray V, Pae V, Sarvadhavabhatla S, Beltran F, Gill G, Lynch K, Yun C, Maguire C, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Viera-Green CA, Spellman SR, Langton DJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Gras S, Maiers M, Hollenbach JA. Augusto DG, et al. Among authors: lee s. medRxiv [Preprint]. 2022 Oct 12:2021.05.13.21257065. doi: 10.1101/2021.05.13.21257065. medRxiv. 2022. Update in: Nature. 2023 Aug;620(7972):128-136. doi: 10.1038/s41586-023-06331-x. PMID: 34031661 Free PMC article. Updated. Preprint.
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