Zeng X - Search Results

1

Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling.

Guo G, Gao M, Gao X, Zhu B, Huang J, Tu X, Kim W, Zhao F, Zhou Q, Zhu S, Wu Z, Yan Y, Zhang Y, Zeng X, Zhu Q, Yin P, Luo K, Sun J, Deng M, Lou Z. Guo G, et al. Among authors: zeng x. Nat Commun. 2021 Apr 12;12(1):2187. doi: 10.1038/s41467-021-22484-7. Nat Commun. 2021. PMID: 33846346 Free PMC article.

2

The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.

Yan Y, Xu Z, Huang J, Guo G, Gao M, Kim W, Zeng X, Kloeber JA, Zhu Q, Zhao F, Luo K, Lou Z. Yan Y, et al. Among authors: zeng x. Nucleic Acids Res. 2020 Dec 16;48(22):12711-12726. doi: 10.1093/nar/gkaa1090. Nucleic Acids Res. 2020. PMID: 33237263 Free PMC article.

3

USP13 regulates the replication stress response by deubiquitinating TopBP1.

Kim W, Zhao F, Gao H, Qin S, Hou J, Deng M, Kloeber JA, Huang J, Zhou Q, Guo G, Gao M, Zeng X, Zhu S, Tu X, Wu Z, Zhang Y, Yin P, Kaufmann SH, Luo K, Lou Z. Kim W, et al. Among authors: zeng x. DNA Repair (Amst). 2021 Apr;100:103063. doi: 10.1016/j.dnarep.2021.103063. Epub 2021 Feb 6. DNA Repair (Amst). 2021. PMID: 33592542 Free PMC article.

4

LRRK2 inhibition potentiates PARP inhibitor cytotoxicity through inhibiting homologous recombination-mediated DNA double strand break repair.

Chen L, Hou J, Zeng X, Guo Q, Deng M, Kloeber JA, Tu X, Zhao F, Wu Z, Huang J, Luo K, Kim W, Lou Z. Chen L, et al. Among authors: zeng x. Clin Transl Med. 2021 Mar;11(3):e341. doi: 10.1002/ctm2.341. Clin Transl Med. 2021. PMID: 33784003 Free PMC article.

5

MET Amplification Attenuates Lung Tumor Response to Immunotherapy by Inhibiting STING.

Zhang Y, Yang Q, Zeng X, Wang M, Dong S, Yang B, Tu X, Wei T, Xie W, Zhang C, Guo Q, Kloeber JA, Cao Y, Guo G, Zhou Q, Zhao F, Huang J, Liu L, Zhang K, Wang M, Yin P, Luo K, Deng M, Kim W, Hou J, Shi Y, Zhu Q, Chen L, Hu S, Yue J, Pi G, Lou Z. Zhang Y, et al. Among authors: zeng x. Cancer Discov. 2021 Nov;11(11):2726-2737. doi: 10.1158/2159-8290.CD-20-1500. Epub 2021 Jun 7. Cancer Discov. 2021. PMID: 34099454

6

METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma.

Zeng X, Zhao F, Cui G, Zhang Y, Deshpande RA, Chen Y, Deng M, Kloeber JA, Shi Y, Zhou Q, Zhang C, Hou J, Kim W, Tu X, Yan Y, Xu Z, Chen L, Gao H, Guo G, Liu J, Zhu Q, Cao Y, Huang J, Wu Z, Zhu S, Yin P, Luo K, Mer G, Paull TT, Yuan J, Tao K, Lou Z. Zeng X, et al. Nat Cancer. 2022 Sep;3(9):1088-1104. doi: 10.1038/s43018-022-00429-3. Epub 2022 Sep 22. Nat Cancer. 2022. PMID: 36138131

7

Targeting BCL6 in Gastrointestinal Stromal Tumor Promotes p53-Mediated Apoptosis to Enhance the Antitumor Activity of Imatinib.

Zeng X, Zhao F, Jia J, Ma X, Jiang Q, Zhang R, Li C, Wang T, Liu W, Hao Y, Tao K, Lou Z, Zhang P. Zeng X, et al. Cancer Res. 2023 Nov 1;83(21):3624-3635. doi: 10.1158/0008-5472.CAN-23-0082. Cancer Res. 2023. PMID: 37556508

8

Targeting CENP-E augments immunotherapy in non-small cell lung cancer via stabilizing PD-L1.

Liang J, Tian C, Liu L, Zeng X, Zhang Y. Liang J, et al. Among authors: zeng x. Int Immunopharmacol. 2024 Jan 5;126:111294. doi: 10.1016/j.intimp.2023.111294. Epub 2023 Dec 4. Int Immunopharmacol. 2024. PMID: 38043265

9

Intratumoral microbiome promotes liver metastasis and dampens adjuvant imatinib treatment in gastrointestinal stromal tumor.

Li Y, Zhang R, Fu C, Jiang Q, Zhang P, Zhang Y, Chen J, Tao K, Chen WH, Zeng X. Li Y, et al. Among authors: zeng x. Cancer Lett. 2024 Oct 1;601:217149. doi: 10.1016/j.canlet.2024.217149. Epub 2024 Aug 8. Cancer Lett. 2024. PMID: 39117066

10

Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells.

Li C, Shen Q, Zhang P, Wang T, Liu W, Li R, Ma X, Zeng X, Yin Y, Tao K. Li C, et al. Among authors: zeng x. J Exp Clin Cancer Res. 2021 Oct 8;40(1):315. doi: 10.1186/s13046-021-02120-4. J Exp Clin Cancer Res. 2021. PMID: 34625086 Free PMC article.

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