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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Dentro SC, Leshchiner I, Haase K, Tarabichi M, Wintersinger J, Deshwar AG, Yu K, Rubanova Y, Macintyre G, Demeulemeester J, Vázquez-García I, Kleinheinz K, Livitz DG, Malikic S, Donmez N, Sengupta S, Anur P, Jolly C, Cmero M, Rosebrock D, Schumacher SE, Fan Y, Fittall M, Drews RM, Yao X, Watkins TBK, Lee J, Schlesner M, Zhu H, Adams DJ, McGranahan N, Swanton C, Getz G, Boutros PC, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Martincorena I, Markowetz F, Mustonen V, Yuan K, Gerstung M, Spellman PT, Wang W, Morris QD, Wedge DC, Van Loo P; PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium. Dentro SC, et al. Among authors: markowetz f. Cell. 2021 Apr 15;184(8):2239-2254.e39. doi: 10.1016/j.cell.2021.03.009. Epub 2021 Apr 7. Cell. 2021. PMID: 33831375 Free PMC article.
Dissecting cancer heterogeneity--an unsupervised classification approach.
Wang X, Markowetz F, De Sousa E Melo F, Medema JP, Vermeulen L. Wang X, et al. Among authors: markowetz f. Int J Biochem Cell Biol. 2013 Nov;45(11):2574-9. doi: 10.1016/j.biocel.2013.08.014. Epub 2013 Sep 1. Int J Biochem Cell Biol. 2013. PMID: 24004832 Review.
Phylogenetic quantification of intra-tumour heterogeneity.
Schwarz RF, Trinh A, Sipos B, Brenton JD, Goldman N, Markowetz F. Schwarz RF, et al. Among authors: markowetz f. PLoS Comput Biol. 2014 Apr 17;10(4):e1003535. doi: 10.1371/journal.pcbi.1003535. eCollection 2014 Apr. PLoS Comput Biol. 2014. PMID: 24743184 Free PMC article.
Cancer evolution: mathematical models and computational inference.
Beerenwinkel N, Schwarz RF, Gerstung M, Markowetz F. Beerenwinkel N, et al. Among authors: markowetz f. Syst Biol. 2015 Jan;64(1):e1-25. doi: 10.1093/sysbio/syu081. Epub 2014 Oct 7. Syst Biol. 2015. PMID: 25293804 Free PMC article. Review.
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.
Schwarz RF, Ng CK, Cooke SL, Newman S, Temple J, Piskorz AM, Gale D, Sayal K, Murtaza M, Baldwin PJ, Rosenfeld N, Earl HM, Sala E, Jimenez-Linan M, Parkinson CA, Markowetz F, Brenton JD. Schwarz RF, et al. Among authors: markowetz f. PLoS Med. 2015 Feb 24;12(2):e1001789. doi: 10.1371/journal.pmed.1001789. eCollection 2015 Feb. PLoS Med. 2015. PMID: 25710373 Free PMC article.
How Subclonal Modeling Is Changing the Metastatic Paradigm.
Macintyre G, Van Loo P, Corcoran NM, Wedge DC, Markowetz F, Hovens CM. Macintyre G, et al. Among authors: markowetz f. Clin Cancer Res. 2017 Feb 1;23(3):630-635. doi: 10.1158/1078-0432.CCR-16-0234. Epub 2016 Nov 18. Clin Cancer Res. 2017. PMID: 27864419 Review.
Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors.
Rye IH, Trinh A, Saetersdal AB, Nebdal D, Lingjaerde OC, Almendro V, Polyak K, Børresen-Dale AL, Helland Å, Markowetz F, Russnes HG. Rye IH, et al. Among authors: markowetz f. Mol Oncol. 2018 Nov;12(11):1838-1855. doi: 10.1002/1878-0261.12375. Epub 2018 Sep 21. Mol Oncol. 2018. PMID: 30133130 Free PMC article.
147 results