Giacomini D - Search Results

1

N-Thio-β-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.

Martelli G, Pessatti TB, Steiner EM, Cirillo M, Caso C, Bisognin F, Landreh M, Monte PD, Giacomini D, Schnell R. Martelli G, et al. Among authors: giacomini d. Cell Chem Biol. 2021 Sep 16;28(9):1321-1332.e5. doi: 10.1016/j.chembiol.2021.03.008. Epub 2021 Apr 6. Cell Chem Biol. 2021. PMID: 33826941 Free article.

2

New polyphenolic beta-lactams with antioxidant activity.

Cainelli G, Angeloni C, Cervellati R, Galletti P, Giacomini D, Hrelia S, Sinisi R. Cainelli G, et al. Among authors: giacomini d. Chem Biodivers. 2008 May;5(5):811-29. doi: 10.1002/cbdv.200890077. Chem Biodivers. 2008. PMID: 18493967

3

Monocyclic β-lactams: new structures for new biological activities.

Galletti P, Giacomini D. Galletti P, et al. Among authors: giacomini d. Curr Med Chem. 2011;18(28):4265-83. doi: 10.2174/092986711797200480. Curr Med Chem. 2011. PMID: 21861821 Review.

4

Monocyclic β-lactams as antibacterial agents: facing antioxidant activity of N-methylthio-azetidinones.

Cervellati R, Galletti P, Greco E, Cocuzza CE, Musumeci R, Bardini L, Paolucci F, Pori M, Soldati R, Giacomini D. Cervellati R, et al. Among authors: giacomini d. Eur J Med Chem. 2013 Feb;60:340-9. doi: 10.1016/j.ejmech.2012.12.024. Epub 2012 Dec 20. Eur J Med Chem. 2013. PMID: 23314047

5

New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins.

Baiula M, Galletti P, Martelli G, Soldati R, Belvisi L, Civera M, Dattoli SD, Spampinato SM, Giacomini D. Baiula M, et al. Among authors: giacomini d. J Med Chem. 2016 Nov 10;59(21):9721-9742. doi: 10.1021/acs.jmedchem.6b00576. Epub 2016 Oct 21. J Med Chem. 2016. PMID: 27726366 Free article.

6

Monocyclic β-lactams loaded on hydroxyapatite: new biomaterials with enhanced antibacterial activity against resistant strains.

Giacomini D, Torricelli P, Gentilomi GA, Boanini E, Gazzano M, Bonvicini F, Benetti E, Soldati R, Martelli G, Rubini K, Bigi A. Giacomini D, et al. Sci Rep. 2017 Jun 2;7(1):2712. doi: 10.1038/s41598-017-02943-2. Sci Rep. 2017. PMID: 28578416 Free PMC article.

7

Design and Synthesis of 4-Alkylidene-β-lactams: Benzyl- and Phenethyl-carbamates as Key Fragments to Switch on Antibacterial Activity.

Giacomini D, Martelli G, Piccichè M, Calaresu E, Cocuzza CE, Musumeci R. Giacomini D, et al. ChemMedChem. 2017 Sep 21;12(18):1525-1533. doi: 10.1002/cmdc.201700307. Epub 2017 Aug 31. ChemMedChem. 2017. PMID: 28737008

8

4-Alkyliden-azetidinones modified with plant derived polyphenols: Antibacterial and antioxidant properties.

Giacomini D, Musumeci R, Galletti P, Martelli G, Assennato L, Sacchetti G, Guerrini A, Calaresu E, Martinelli M, Cocuzza C. Giacomini D, et al. Eur J Med Chem. 2017 Nov 10;140:604-614. doi: 10.1016/j.ejmech.2017.09.048. Epub 2017 Sep 23. Eur J Med Chem. 2017. PMID: 28992569

9

Antibacterial and antioxidant activities for natural and synthetic dual-active compounds.

Martelli G, Giacomini D. Martelli G, et al. Among authors: giacomini d. Eur J Med Chem. 2018 Oct 5;158:91-105. doi: 10.1016/j.ejmech.2018.09.009. Epub 2018 Sep 5. Eur J Med Chem. 2018. PMID: 30205261 Review.

10

Chiral β-lactam-based integrin ligands through Lipase-catalysed kinetic resolution and their enantioselective receptor response.

Martelli G, Galletti P, Baiula M, Calcinari L, Boschi G, Giacomini D. Martelli G, et al. Among authors: giacomini d. Bioorg Chem. 2019 Jul;88:102975. doi: 10.1016/j.bioorg.2019.102975. Epub 2019 May 9. Bioorg Chem. 2019. PMID: 31102807

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