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ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model.
Vandyck K, Abdelnabi R, Gupta K, Jochmans D, Jekle A, Deval J, Misner D, Bardiot D, Foo CS, Liu C, Ren S, Beigelman L, Blatt LM, Boland S, Vangeel L, Dejonghe S, Chaltin P, Marchand A, Serebryany V, Stoycheva A, Chanda S, Symons JA, Raboisson P, Neyts J. Vandyck K, et al. Among authors: dejonghe s. Biochem Biophys Res Commun. 2021 May 28;555:134-139. doi: 10.1016/j.bbrc.2021.03.096. Epub 2021 Mar 26. Biochem Biophys Res Commun. 2021. PMID: 33813272 Free PMC article.
In vitro activity of itraconazole against SARS-CoV-2.
Van Damme E, De Meyer S, Bojkova D, Ciesek S, Cinatl J, De Jonghe S, Jochmans D, Leyssen P, Buyck C, Neyts J, Van Loock M. Van Damme E, et al. J Med Virol. 2021 Jul;93(7):4454-4460. doi: 10.1002/jmv.26917. J Med Virol. 2021. PMID: 33666253 Free PMC article.
123 results