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BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Mills RJ, Humphrey SJ, Fortuna PRJ, Lor M, Foster SR, Quaife-Ryan GA, Johnston RL, Dumenil T, Bishop C, Rudraraju R, Rawle DJ, Le T, Zhao W, Lee L, Mackenzie-Kludas C, Mehdiabadi NR, Halliday C, Gilham D, Fu L, Nicholls SJ, Johansson J, Sweeney M, Wong NCW, Kulikowski E, Sokolowski KA, Tse BWC, Devilée L, Voges HK, Reynolds LT, Krumeich S, Mathieson E, Abu-Bonsrah D, Karavendzas K, Griffen B, Titmarsh D, Elliott DA, McMahon J, Suhrbier A, Subbarao K, Porrello ER, Smyth MJ, Engwerda CR, MacDonald KPA, Bald T, James DE, Hudson JE. Mills RJ, et al. Among authors: rudraraju r. Cell. 2021 Apr 15;184(8):2167-2182.e22. doi: 10.1016/j.cell.2021.03.026. Epub 2021 Mar 16. Cell. 2021. PMID: 33811809 Free PMC article.
Antibody titres elicited by the 2018 seasonal inactivated influenza vaccine decline by 3 months post-vaccination but persist for at least 6 months.
Mordant FL, Price OH, Rudraraju R, Slavin MA, Marshall C, Worth LJ, Peck H, Barr IG, Sullivan SG, Subbarao K. Mordant FL, et al. Among authors: rudraraju r. Influenza Other Respir Viruses. 2023 Jan;17(1):e13072. doi: 10.1111/irv.13072. Epub 2022 Nov 30. Influenza Other Respir Viruses. 2023. PMID: 36451293 Free PMC article.
Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment.
Rudraraju R, Gartner MJ, Neil JA, Stout ES, Chen J, Needham EJ, See M, Mackenzie-Kludas C, Yang Lee LY, Wang M, Pointer H, Karavendzas K, Abu-Bonsrah D, Drew D, Yang Sun YB, Tan JP, Sun G, Salavaty A, Charitakis N, Nim HT, Currie PD, Tham WH, Porrello E, Polo JM, Humphrey SJ, Ramialison M, Elliott DA, Subbarao K. Rudraraju R, et al. Stem Cell Reports. 2023 Jun 13;18(6):1308-1324. doi: 10.1016/j.stemcr.2023.05.007. Stem Cell Reports. 2023. PMID: 37315523 Free PMC article.
A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts.
Chen J, Neil JA, Tan JP, Rudraraju R, Mohenska M, Sun YBY, Walters E, Bediaga NG, Sun G, Zhou Y, Li Y, Drew D, Pymm P, Tham WH, Wang Y, Rossello FJ, Nie G, Liu X, Subbarao K, Polo JM. Chen J, et al. Among authors: rudraraju r. Nat Cell Biol. 2023 Aug;25(8):1223-1234. doi: 10.1038/s41556-023-01182-0. Epub 2023 Jul 13. Nat Cell Biol. 2023. PMID: 37443288 Free PMC article.
Off-target effects of bacillus Calmette-Guérin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19.
Messina NL, Germano S, McElroy R, Rudraraju R, Bonnici R, Pittet LF, Neeland MR, Nicholson S, Subbarao K, Curtis N; BRACE trial. Messina NL, et al. Among authors: rudraraju r. Clin Transl Immunology. 2022 Apr 22;11(4):e1387. doi: 10.1002/cti2.1387. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35573165 Free PMC article.
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